CAS 2026-48-4

1-Butanol, 2-amino-3-methyl-, (2S)-

Formel: C₅H₁₃NO

InChl: InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3/t5-/m1/s1

InChI Key: InChIKey=NWYYWIJOWOLJNR-RXMQYKEDSA-N

SMILES: [C@H](C(C)C)(CO)N

Synonyme:

• (+)-(S)-Valinol
• (+)-2-Amino-3-methyl-1-butanol
• (+)-Valinol
• (2S)-1-Hydroxy-3-methylbutan-2-amine
• (2S)-2-Amino-3-methyl-1-butanol
• (2S)-Valinol
• (S)-(+)-2-Amino-3-methyl-1-butanol
• (S)-2-Amino-3-methylbutanol
• 1-Butanol, 2-amino-3-methyl-, (S)-
• 1-Butanol, 2-amino-3-methyl-, <span class="text-smallcaps">L</span>-
• 1-Butanol, 2-amino-3-methyl-, L-
• <span class="text-smallcaps">L</span>-Valinol
• Butanol, 2-Amino-3-Methyl, (S)-(+)-
• L-2-amino-3-methylbutan-1-ol
• L-2-amino-3-methylbutane-1-ol
• L-2-amino-3-metilbutan-1-ol
• L-Valinol
• Nsc 322922
• [(S)-1-(Hydroxymethyl)-2-methylpropyl]amine
• Valinol,97%
• (2R)-2-amino-3-methylbutan-1-ol
• 1-Butanol, 2-amino-3-methyl-, (2S)-
• H-Val-ol
• (S)-2-Amino-3-methyl-butanol

L-Valinol

CAS: 2026-48-4

Formel: C₅H₁₃NO

Reinheit: >97.0%(GC)(T)

Farbe und Form: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molekulargewicht: 103.17

Ref: 3B-V0058

L-(+)-Valinol, 97%

CAS: 2026-48-4

L-(+)-Valinol reacts with aldehydes and nitriles to form imines and oxazolines, respectively, for asymmetric synthesis. It is also used for preparation of 4-isopropyloxazolidinones, employed in stereocontrolled aldol and alkylation reactions, synthesis of chiral 2-thiazolidinethiones for aldol react

Formel: C₅H₁₃NO

Reinheit: 97%

Farbe und Form: Colourless/white to yellow, liquid/low melting solid

Molekulargewicht: 103.17

Ref: 02-L11300

L-Valinol

CAS: 2026-48-4

M03447 - L-Valinol

Formel: C₅H₁₃NO

Reinheit: 95%

Farbe und Form: Liquid

Molekulargewicht: 103.165

Ref: 10-M03447

(S)-(+)-2-Amino-3-methyl-1-butanol

CAS: 2026-48-4

(S)-(+)-2-Amino-3-methyl-1-butanol

Formel: C₅H₁₃NO

Reinheit: 97%

Farbe und Form: Solid

Molekulargewicht: 103.16281

Ref: 54-OR5874

L-Valinol

CAS: 2026-48-4

Formel: C₅H₁₃NO

Farbe und Form: Neat

Molekulargewicht: 103.163

Ref: 86-MM3372.23

L-Valinol

CAS: 2026-48-4

Formel: C₅H₁₃NO

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 103.1628

Ref: IN-DA0028CI

L-Valinol

CAS: 2026-48-4

(S)-2-Amino-3-methylbutan-1-ol

Formel: C₅H₁₃NO

Reinheit: 98%

Molekulargewicht: 103.16

Ref: IN-DG19265

L-Valinol

CAS: 2026-48-4

Formel: C₅H₁₃NO

Reinheit: ≥ 97.0%

Farbe und Form: Colourless to white or pale yellow solid, crystals or liquid

Molekulargewicht: 103.17

Ref: 7W-GM8064

L-Valinol

CAS: 2026-48-4

L-Valinol is a model system that is used to study the reaction of aziridines with oxygen nucleophiles. It has been shown that this reaction proceeds through the formation of an intermediate, hydrogen tartrate, followed by a second step with nitrogen atoms as the nucleophile and alcohol residue as the substrate. The use of L-valinol in asymmetric synthesis was also demonstrated. In this process, amides were obtained with high enantioselectivity by reacting L-valinol with amines in acidic conditions. This synthetic pathway was found to be synergic with other reactions, such as nitroolefination and benzoylation.

Formel: C₅H₁₃NO

Reinheit: Min. 95%

Farbe und Form: Solidified Mass

Molekulargewicht: 103.16 g/mol

Ref: 3D-FV10652

(S)-2-Amino-3-methylbutan-1-ol

CAS: 2026-48-4

(S)-2-Amino-3-methylbutan-1-ol

Formel: C₅H₁₃NO

Reinheit: 97%

Molekulargewicht: 103.16

Ref: IN-DG2509

L-Valinol

Kontrolliertes Produkt

CAS: 2026-48-4

Applications L-Valinol is used as a reagent in the synthesis of simple 1,3-thiazolidine-2-thione derivatives which can exhibit fungicidal activity. L-Valinol is also used as a reagent in the synthesis of small-molecule inhibitors of MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for the treatment of cancer.
References Chen, N., et al.: Phosphorus Sulfur, 190, 112 (2015); Zhao, Y., et al.: J. Med. Chem., 58, 1038 (2015)

Formel: C₅H₁₃NO

Farbe und Form: Neat

Molekulargewicht: 103.163

Ref: TR-V094340