CAS 2059952-75-7
:Formel:C28H29NO6
InChl:InChI=1S/C28H29NO6/c1-31-23-14-20(15-24(18-23)32-2)7-6-19-8-11-22(12-9-19)29-27(30)13-10-21-16-25(33-3)28(35-5)26(17-21)34-4/h6-18H,1-5H3,(H,29,30)/b7-6+,13-10+
InChI Key:KOZAEBHIXYBHKA-FCXQYMQBSA-N
SMILES:COC1=CC(=CC(=C1)/C=C/C2=CC=C(C=C2)NC(=O)/C=C/C3=CC(=C(C(=C3)OC)OC)OC)OC
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STAT3-IN-1
CAS:STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumorFormel:C28H29NO6Reinheit:95.89% - 98.13%Farbe und Form:SolidMolekulargewicht:475.533(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
CAS:(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamideFormel:C28H29NO6Reinheit:98%Molekulargewicht:475.53(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
CAS:Formel:C28H29NO6Reinheit:98%Farbe und Form:SolidMolekulargewicht:475.5330STAT3-IN-1
CAS:(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamideFormel:C28H29NO6Reinheit:98%Molekulargewicht:475.53(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
CAS:Reinheit:98%Molekulargewicht:475.5409851STAT3-IN-1
CAS:STAT3-IN-1 is a small molecule that inhibits the activation of the transcription factor STAT3. STAT3 is involved in the regulation of cancer cell proliferation and survival, as well as the suppression of inflammation. STAT3-IN-1 has been shown to inhibit tumor growth by blocking IL-10 production and attenuating tissue inhibitor of metalloproteinase (TIMP)-1 expression. It also inhibits chemoresistance in breast cancer cells by reducing NF-κB activity, which leads to increased apoptosis and decreased proliferation rates. Additionally, STAT3-IN-1 has been shown to reduce tumor size in mice xenografts, enhance tissue regeneration and improve prognosis.
Formel:C28H29NO6Reinheit:Min. 95%Molekulargewicht:475.5 g/mol
