CAS 2097002-59-8

Formel: C20H21FN6O

InChl: InChI=1S/C20H21FN6O/c1-12-4-5-16-14(9-13(21)10-22-16)17-3-2-7-26(17)18-6-8-27-19(25-18)15(11-23-27)20(28)24-12/h6,8-12,17H,2-5,7H2,1H3,(H,24,28)/t12-,17+/m0/s1

InChI Key: OEBIHOVSAMBXIB-YVEFUNNKSA-N

SMILES: C[C@H]1CCC2=C(C=C(C=N2)F)[C@H]3CCCN3C4=NC5=C(C=NN5C=C4)C(=O)N1

(R,S)-Selitrectinib

CAS: 2097002-59-8

(R,S)-Selitrectinib (compound 17) is a Trk inhibitor that shows activity against cancers with NTRK1, NTRK2, or NTRK3 gene mutations that confer resistance to other Trk inhibitors. It is suitable for research involving Trk inhibitor-resistant cancers.

Formel: C₂₀H₂₁FN₆O

Molekulargewicht: 380.42

Ref: TM-T218798