CAS 2163060-83-9

Formel: C28H34ClN9O3S

InChl: InChI=1S/C28H34ClN9O3S/c1-19(2)42(39,40)26-8-6-5-7-24(26)31-27-22(29)16-30-28(33-27)32-23-10-9-21(15-25(23)41-4)38-18-20(34-35-38)17-37-13-11-36(3)12-14-37/h5-10,15-16,18-19H,11-14,17H2,1-4H3,(H2,30,31,32,33)

InChI Key: MYBIYOGYGXIDJG-UHFFFAOYSA-N

SMILES: CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4C=C(N=N4)CN5CCN(CC5)C)OC

WY-135

CAS: 2163060-83-9

Wy-135 is a potential drug that has shown inhibition of cyclin-dependent kinases. It has been shown to inhibit G1 phase cell cycle progression and induce apoptosis in a dose-dependent manner. Wy-135 has also been shown to inhibit the growth of cancer cells in culture. This compound may be useful as an anti-cancer agent and chemotherapeutic drug. Wy-135 inhibits cellular proliferation and induces apoptosis by inhibiting protein synthesis, DNA replication, and enzyme activity. The cocrystal structure of Wy-135 with cyclin was determined and its inhibitory activities were analyzed by cycle analysis. Wy-135's effects on cancer cells are due to its ability to inhibit the enzymatic activities involved in cell division, including protein synthesis and DNA replication.

Formel: C₂₈H₃₄ClN₉O₃S

Reinheit: Min. 95%

Molekulargewicht: 612.1 g/mol

Ref: 3D-NLD06083

WY-135

CAS: 2163060-83-9

WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 nM, respectively).

Formel: C₂₈H₃₄ClN₉O₃S

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 612.15

Ref: TM-T13351