CAS 2247064-44-2

Formel: C23H22N6O3

InChl: InChI=1S/C23H22N6O3/c30-22(27-8-10-32-11-9-27)15-4-7-18-16(12-15)13-28(23(18)31)20-3-1-2-19(25-20)21-26-24-14-29(21)17-5-6-17/h1-4,7,12,14,17H,5-6,8-11,13H2

InChI Key: KOULFMRALARHIM-UHFFFAOYSA-N

SMILES: C1CC1N2C=NN=C2C3=NC(=CC=C3)N4CC5=C(C4=O)C=CC(=C5)C(=O)N6CCOCC6

ASK1-IN-11

CAS: 2247064-44-2

ASK1-IN-11 (Compound 7) is an inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of less than 200 nM. It also exhibits inhibitory activity against TNF-α, MYLK/MLCK kinase, and the hERG potassium ion channel. ASK1-IN-11 can be utilized in inflammation research.

Formel: C₂₃H₂₂N₆O₃

Molekulargewicht: 430.47

Ref: TM-T213510