CAS 2306363-09-5

Formel: C22H23N3O5

InChl: InChI=1S/C22H23N3O5/c1-4-15-6-5-7-16(12-15)23-21-17-13-19(29-10-8-27-2)20(30-11-9-28-3)14-18(17)24-22(26)25-21/h1,5-7,12-14H,8-11H2,2-3H3,(H2,23,24,25,26)

InChI Key: SPIIJDKCIZIHNE-UHFFFAOYSA-N

SMILES: COCCOC1=C(C=C2C(=C1)C(=NC(=O)N2)NC3=CC=CC(=C3)C#C)OCCOC

2-Hydroxyerlotinib

Kontrolliertes Produkt

CAS: 2306363-09-5

Applications 2-Hydroxyerlotinib is an impurity of Erlotinib (E625000). Erlotinib is a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. An antineoplastic.
References Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997), Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001), Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004), Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005),

Formel: C₂₂H₂₃N₃O₅

Farbe und Form: Neat

Molekulargewicht: 409.44

Ref: TR-H101040