CAS 2306388-65-6

Formel: C47H50F6N6O7S

InChl: InChI=1S/C47H50F6N6O7S/c1-27-40(67-26-57-27)30-12-9-28(10-13-30)23-56-43(63)36-21-34(60)24-59(36)44(64)41(45(2,3)4)58-39(61)8-6-7-17-55-42(62)32(22-54)18-29-11-16-37(38(19-29)65-5)66-25-31-14-15-33(46(48,49)50)20-35(31)47(51,52)53/h9-16,18-20,26,34,36,41,60H,6-8,17,21,23-25H2,1-5H3,(H,55,62)(H,56,63)(H,58,61)/b32-18+/t34-,36+,41-/m1/s1

InChI Key: POTUUCUOBIVSIX-BDUCEWPUSA-N

SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCNC(=O)/C(=C/C4=CC(=C(C=C4)OCC5=C(C=C(C=C5)C(F)(F)F)C(F)(F)F)OC)/C#N)O

(2S,4R)-1-((S)-2-(5-((E)-3-(4-((2,4-Bis(trifluoromethyl)benzyl)oxy)-3-methoxyphenyl)-2-cyanoacrylamido)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carb

CAS: 2306388-65-6

(2S,4R)-1-((S)-2-(5-((E)-3-(4-((2,4-Bis(trifluoromethyl)benzyl)oxy)-3-methoxyphenyl)-2-cyanoacrylamido)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carb

Formel: C₄₇H₅₀F₆N₆O₇S

Reinheit: 98%

Molekulargewicht: 957.01

Ref: 54-PC1006497

PROTAC ERRα Degrader-3

CAS: 2306388-65-6

PROTAC ERRα Degrader-3 is a potent, selective VHL-based PROTAC that degrades ERRα by over 80% at 30 nM, with no activity against ERRβ or ERRγ.

Formel: C₄₇H₅₀F₆N₆O₇S

Farbe und Form: Solid

Molekulargewicht: 956.991

Ref: TM-T39837

(2S,4R)-1-[(2S)-2-{5-[(2E)-3-(4-{[2,4-bis(trifluoromethyl)phenyl]methoxy}-3-methoxyphenyl)-2-cyanoprop-2-enamido]pentanamido}-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide

CAS: 2306388-65-6

Formel: C₄₇H₅₀F₆N₆O₇S

Reinheit: 98%

Molekulargewicht: 956.9913

Ref: IN-DA029J3W

ERRα PROTAC compound I

CAS: 2306388-65-6

(2S,4R)-1-((S)-2-(5-((E)-3-(4-((2,4-Bis(trifluoromethyl)benzyl)oxy)-3-methoxyphenyl)-2-cyanoacrylamido)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

Formel: C₄₇H₅₀F₆N₆O₇S

Reinheit: 98%

Molekulargewicht: 956.99

Ref: IN-DG01440141