CAS 2479961-45-8

Formel: C26H29N9

InChl: InChI=1S/C26H29N9/c1-16-4-5-19(11-27-16)13-35-21-10-22(35)15-34(14-21)25-7-6-20(12-28-25)26-29-17(2)8-23(31-26)30-24-9-18(3)32-33-24/h4-9,11-12,21-22H,10,13-15H2,1-3H3,(H2,29,30,31,32,33)

InChI Key: CWNFJUJYLGXPEP-UHFFFAOYSA-N

SMILES: CC1=NC=C(C=C1)CN2C3CC2CN(C3)C4=NC=C(C=C4)C5=NC(=CC(=N5)NC6=NNC(=C6)C)C

RET-IN-28

CAS: 2479961-45-8

RET-IN-28 (Compound 16) is an inhibitor of RET (a transmembrane receptor tyrosine kinase). It specifically inhibits the activity of a mutant RET enzyme (RET-V804M) and is utilized in cancer research.

Formel: C₂₆H₂₉N₉

Farbe und Form: Solid

Molekulargewicht: 467.57

Ref: TM-T203439