CAS 249762-74-1

(5-BUTANOATE-1H-2-INDOLYL)(1H-2-INDOLYL)-METHANONE

Formel: C₂₁H₁₈N₂O₃

InChl: InChI=1S/C21H18N2O3/c1-2-5-20(24)26-15-8-9-17-14(10-15)12-19(23-17)21(25)18-11-13-6-3-4-7-16(13)22-18/h3-4,6-12,22-23H,2,5H2,1H3

InChI Key: CZDUJGOCEPWCNA-UHFFFAOYSA-N

SMILES: CCCC(=O)OC1=CC2=C(C=C1)NC(=C2)C(=O)C3=CC4=CC=CC=C4N3

Synonyme:

• PDGF RECEPTOR TYROSINE KINASE INHIBITOR II
• [2-(1H-2-INDOLYCARBONYL)-1H-5-INDOLYL]BUTANOATE
• (5-BUTANOATE-1H-2-INDOLYL)(1H-2-INDOLYL)-METHANONE
• Butanoic acid, 2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl ester
• D-65476
• [2-(1H-2-INDOLYLCARBONYL)-1H-5-INDOLYL]BUTANOATE
• PDGFR Tyrosine Kinase Inhibitor II

D-65476

CAS: 249762-74-1

D-65476 is a type III receptor tyrosine kinase (Flt3) inhibitor. It inhibits the proliferation of TEL-Flt3 transfected BA/F3 cells in the absence of IL-3, with an IC50 of 0.2 μM, and is useful for researching Flt3-driven leukemia.

Formel: C₂₁H₁₈N₂O₃

Farbe und Form: Solid

Molekulargewicht: 346.38

Ref: TM-T210001