CAS 2570985-89-4

NA

Formel: C₂₆H₃₂N₈O₂

InChl: InChI=1S/C26H32N8O2/c1-18(2)34-17-28-30-24(34)22-5-4-6-23(29-22)33-16-15-32(26(33)36)21-9-7-20(8-10-21)31-13-11-19(12-14-31)25(35)27-3/h4-10,17-19H,11-16H2,1-3H3,(H,27,35)

InChI Key: PFWQYMLTRDLYDO-UHFFFAOYSA-N

SMILES: CC(C)N1C=NN=C1C2=NC(=CC=C2)N3CCN(C3=O)C4=CC=C(C=C4)N5CCC(CC5)C(=O)NC

Synonyme:

• [Synonyms]

ASK1-IN-8

CAS: 2570985-89-4

ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.

Formel: C₂₆H₃₂N₈O₂

Farbe und Form: Solid

Molekulargewicht: 488.585

Ref: TM-T206247