CAS 2576427-49-9

VS3

CAS: 2576427-49-9

VS3 is an inhibitor of the YAP-TEAD interaction. By directly binding to the TEAD4 Interface 3 (Kd = 6 μM), VS3 disrupts the interaction between YAP and TEAD. It exhibits antiproliferative activity against HT29, HCT116, and A2780 cells. VS3 is useful for studying colorectal adenocarcinoma and ovarian cancer.

Formel: C₂₁H₂₁N₃O₃

Molekulargewicht: 363.42

Ref: TM-T214392