CAS 2648279-77-8

Formel: C25H24N6O2

InChl: InChI=1S/C25H24N6O2/c1-25(2,3)22-12-24(33-30-22)29-23(32)10-16-4-7-19(8-5-16)31-15-26-20-11-17(6-9-21(20)31)18-13-27-28-14-18/h4-9,11-15H,10H2,1-3H3,(H,27,28)(H,29,32)

InChI Key: KLCBEXKZLLKSAW-UHFFFAOYSA-N

SMILES: CC(C)(C)C1=NOC(=C1)NC(=O)CC2=CC=C(C=C2)N3C=NC4=C3C=CC(=C4)C5=CNN=C5

Multi-kinase inhibitor 4

CAS: 2648279-77-8

Multi-kinase inhibitor 4 (compound 14) serves as an orally effective inhibitor targeting FLT1, KDR, FLT3, FLT4, PDGFRα, and PDGFRβ, exhibiting IC₅₀ values of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, and 0.89 nM respectively. This compound plays a crucial role in cancer research.

Formel: C₂₅H₂₄N₆O₂

Farbe und Form: Solid

Molekulargewicht: 440.50

Ref: TM-T201144