CAS 2796279-20-2

Formel: C29H36N6O4S

InChl: InChI=1S/C29H36N6O4S/c1-4-5-25(36)35-16-23(17-35)33-8-6-21(7-9-33)22-14-19(2)27-24(15-22)32-28-26(20(3)39-27)29(31-18-30-28)34-10-12-40(37,38)13-11-34/h14-15,18,20-21,23H,6-13,16-17H2,1-3H3,(H,30,31,32)/t20-/m1/s1

InChI Key: OLEFHQBTXFCZON-HXUWFJFHSA-N

SMILES: CC#CC(=O)N1CC(C1)N2CCC(CC2)C3=CC4=C(C(=C3)C)O[C@@H](C5=C(N4)N=CN=C5N6CCS(=O)(=O)CC6)C

CDK7-IN-33

CAS: 2796279-20-2

CDK7-IN-33 (Compound 148) is a CDK7 inhibitor with a Ki value of 21.75 nM. It suppresses the proliferation of A549 cells expressing CDK7WT, with a pIC50 of 7.37.

Formel: C₂₉H₃₆N₆O₄S

Farbe und Form: Solid

Molekulargewicht: 564.699

Ref: TM-T206088