CAS 2902715-97-1

Formel: C22H24N6O2

InChl: InChI=1S/C22H24N6O2/c1-15-13-30-11-8-28(15)19-12-17(22(14-23)4-9-29-10-5-22)16-2-6-24-21(20(16)26-19)18-3-7-25-27-18/h2-3,6-7,12,15H,4-5,8-11,13H2,1H3,(H,25,27)/t15-/m1/s1

InChI Key: WJWLAISYUDKJBU-OAHLLOKOSA-N

SMILES: C[C@@H]1COCCN1C2=NC3=C(C=CN=C3C4=CC=NN4)C(=C2)C5(CCOCC5)C#N

ATR-IN-32

CAS: 2902715-97-1

ATR-IN-32 is an orally active ATR inhibitor that effectively suppresses the proliferation of MIA PaCa-2 cells. It significantly inhibits tumor growth in mice bearing LOVO and HT-29 xenografts. ATR-IN-32 is applicable for studying cancers mediated by the ATR protein kinase, such as colorectal cancer and pancreatic cancer.

Formel: C₂₂H₂₄N₆O₂

Molekulargewicht: 404.47

Ref: TM-T213577