CAS 2993441-49-7

Formel: C38H40N6O5S

InChl: InChI=1S/C38H40N6O5S/c1-22-8-6-9-23(2)33(22)29-14-32-42-36(41-29)43-50(46,47)28-11-7-10-25(12-28)35(45)44(27(21-48-32)18-38-15-24(16-38)17-38)20-26-19-39-34-30(40-26)13-31(49-34)37(3,4)5/h6-14,19,24,27H,15-18,20-21H2,1-5H3,(H,41,42,43)/t24?,27-,38?/m1/s1

InChI Key: DEZINQVHWHOSGZ-UEXYFGQFSA-N

SMILES: CC1=C(C(=CC=C1)C)C2=CC3=NC(=N2)NS(=O)(=O)C4=CC=CC(=C4)C(=O)N([C@@H](CO3)CC56CC(C5)C6)CC7=CN=C8C(=N7)C=C(O8)C(C)(C)C

CFTR corrector 18

CAS: 2993441-49-7

CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).

Formel: C₃₈H₄₀N₆O₅S

Farbe und Form: Solid

Molekulargewicht: 692.826

Ref: TM-T206874