CAS 3029695-00-6

Formel: C22H24N4O

InChl: InChI=1S/C22H24N4O/c1-2-3-8-19-25-20-21(17-6-4-5-7-18(17)24-22(20)23)26(19)13-15-9-11-16(14-27)12-10-15/h4-7,9-12,27H,2-3,8,13-14H2,1H3,(H2,23,24)

InChI Key: NYWJROIIIXDQML-UHFFFAOYSA-N

SMILES: CCCCC1=NC2=C(N1CC3=CC=C(C=C3)CO)C4=CC=CC=C4N=C2N

TLR7 agonist 20

CAS: 3029695-00-6

TLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 μM for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.

Formel: C₂₂H₂₄N₄O

Molekulargewicht: 360.45

Ref: TM-T88306