CAS 3034813-75-4

Methanone, [(3R,4R)-3,4-dihydroxy-1-pyrrolidinyl][2-[2-methyl-5-[4-(trifluoromethyl)phenoxy]-2H-indazol-7-yl]cyclopropyl]-

Formel: C₂₃H₂₂F₃N₃O₄

InChl: InChI=1S/C23H22F3N3O4/c1-28-9-12-6-15(33-14-4-2-13(3-5-14)23(24,25)26)7-17(21(12)27-28)16-8-18(16)22(32)29-10-19(30)20(31)11-29/h2-7,9,16,18-20,30-31H,8,10-11H2,1H3/t16?,18?,19-,20-/m1/s1

InChI Key: NFYBDIVODIZAPS-PEVDHWGLSA-N

SMILES: CN1C=C2C=C(C=C(C2=N1)C3CC3C(=O)N4C[C@H]([C@@H](C4)O)O)OC5=CC=C(C=C5)C(F)(F)F

Synonyme:

• Methanone, [(3R,4R)-3,4-dihydroxy-1-pyrrolidinyl][2-[2-methyl-5-[4-(trifluoromethyl)phenoxy]-2H-indazol-7-yl]cyclopropyl]-

TEAD-IN-24

CAS: 3034813-75-4

TEAD-IN-24 (Example 65) is a TEAD inhibitor with anticancer activity against non-small cell lung cancer.

Formel: C₂₃H₂₂F₃N₃O₄

Molekulargewicht: 461.44

Ref: TM-T214364