CAS 3036009-40-9

MerTK/Axl-IN-1

CAS: 3036009-40-9

MerTK/Axl-IN-1 (Compound A-910) is a potent and selective dual inhibitor of MerTK/Axl, exhibiting IC50 values of 4.2 nM and 8.8 nM in Ba/F3 cells, and 0.2 nM and 0.9 nM in HTRF cells, respectively. It effectively inhibits pMerTK in vivo and possesses a long half-life and high oral bioavailability.

Formel: C₄₀H₄₇FN₆O₄

Farbe und Form: Solid

Molekulargewicht: 694.84

Ref: TM-T200517