CAS 3084702-28-0

Formel: C21H19N7O

InChl: InChI=1S/C21H19N7O/c22-19(29)13-7-9-14(10-8-13)23-21-24-16-4-2-1-3-15(16)20(26-21)25-18-11-17(27-28-18)12-5-6-12/h1-4,7-12H,5-6H2,(H2,22,29)(H3,23,24,25,26,27,28)

InChI Key: JPEVLFPOUBRGJC-UHFFFAOYSA-N

SMILES: C1CC1C2=CC(=NN2)NC3=NC(=NC4=CC=CC=C43)NC5=CC=C(C=C5)C(=O)N

MKI-3

CAS: 3084702-28-0

MKI-3 is a highly selective MASTL inhibitor with a quinazoline scaffold (IC50 5.72 nM), can inhibit ENSA phosphorylation and activate PP2A, and exhibits antiproliferative and in vivo antitumor activity in breast cancer models.

Formel: C₂₁H₁₉N₇O

Molekulargewicht: 385.42

Ref: TM-T218602