CAS 3104731-13-4

ATM-IN-13

CAS: 3104731-13-4

ATM-IN-13 (A36) is an orally active selective ATM kinase inhibitor with a human IC₅₀ of 0.3 nM. It disrupts the ATM-mediated DNA double-strand break repair signaling pathway, reduces phosphorylation levels of ATM and p53, and inhibits the ATM-dependent DNA damage response. ATM-IN-13 is applicable in colorectal cancer research.

Formel: C₂₇H₃₃N₅O

Molekulargewicht: 443.58

Ref: TM-T218666