CAS 3105688-14-7

NA

Formel: C₁₉H₂₄F₃N₅O₄S₂

InChl: InChI=1S/C19H24F3N5O4S2/c1-11(2)8-12(9-28)23-16-24-17(27-33(3,30)31)26-18(25-16)32-10-15(29)13-6-4-5-7-14(13)19(20,21)22/h4-7,11-12,28H,8-10H2,1-3H3,(H2,23,24,25,26,27)/t12-/m1/s1

InChI Key: KZUPXIPTNNQKQZ-GFCCVEGCSA-N

SMILES: CC(C)C[C@H](CO)NC1=NC(=NC(=N1)SCC(=O)C2=CC=CC=C2C(F)(F)F)NS(=O)(=O)C

Synonyme:

• [Synonyms]

CX3CR1-IN-2

CAS: 3105688-14-7

CX3CR1-IN-2 (Compound 77) is a CX3CR1 inhibitor with an IC50 value of 0.04 μM. It effectively blocks the interaction between CX3CR1 and its ligand, fractalkine (CX3CL1). CX3CR1-IN-2 is useful in research on cardiovascular diseases, such as heart failure and cardiomyopathy.

Formel: C₁₉H₂₄F₃N₅O₄S₂

Molekulargewicht: 507.55

Ref: TM-T214906