CAS 3109321-90-3

TYMJ-01

CAS: 3109321-90-3

TYMJ-01 is a fluorescent probe and an eEF2K degrader. It induces specific, dose-dependent degradation of eEF2K through the ubiquitin-proteasome pathway with a DC50 of 82 nM. TYMJ-01 inhibits the proliferation, migration, and invasion of triple-negative breast cancer cells and enables dynamic fluorescent imaging of eEF2K degradation within these cells. Additionally, it enhances the antitumor activity of Paclitaxel. TYMJ-01 is applicable for research on triple-negative breast cancer.

Formel: C₂₇H₂₈N₆O₄S

Molekulargewicht: 532.61

Ref: TM-T217853