CAS 4276-09-9

D-Valinol

Formel: C₅H₁₃NO

InChl: InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3/t5-/m0/s1

InChI Key: InChIKey=NWYYWIJOWOLJNR-YFKPBYRVSA-N

SMILES: [C@@H](C(C)C)(CO)N

Synonyme:

• (-)-2-Amino-3-methyl-1-butanol
• (-)-Valinol
• (2R)-2-Amino-3-methyl-1-butanol
• (2R)-2-Amino-3-methylbutan-1-ol
• (R)-(-)-2-Amino-3-methyl-1-butanol
• (R)-2-Amino-3-methylbutan-2-ol
• (R)-2-Amino-3-methylbutanol
• (R)-2-amino-3-methylbutan-1-ol
• (R)-Valinol
• 1-Butanol, 2-amino-3-methyl-, (2R)-
• 1-Butanol, 2-amino-3-methyl-, (R)-
• 1-Butanol, 2-amino-3-methyl-, <span class="text-smallcaps">D</span>-
• <span class="text-smallcaps">D</span>-Valinol
• D-valinol (R-2-amino-3-methyl-1-butanol)
• [(R)-1-(Hydroxymethyl)-2-methylpropyl]amine
• 1-Butanol, 2-amino-3-methyl-, D-
• D-Valinol
• D-VALINAL
• (R)-(-)-Z-Amino-3-Methyl-1-Butanol
• H-D-VAL-OL
• D-2-AMINO-3-METHYL-1-BUTANOL
• D-Val-ol
• 2-AMINO-3-METHYLBUTAN-1-OL
• D-(-)-VALINOL 98%

D-Valinol

CAS: 4276-09-9

D-Valinol

Formel: C₅H₁₃NO

Reinheit: 98%

Molekulargewicht: 103.16

Ref: IN-DG9500

D-Valinol

CAS: 4276-09-9

Formel: C₅H₁₃NO

Reinheit: >98.0%(GC)(T)

Farbe und Form: White or Colorless to Light yellow powder to lump to clear liquid

Molekulargewicht: 103.17

Ref: 3B-V0077

D-(-)-Valinol, 98%

CAS: 4276-09-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formel: C₅H₁₃NO

Reinheit: 98%

Farbe und Form: Colorless to white to yellow, Crystals or powder or crystalline powder or fused solid or clear liquid or viscous liquid as melt

Molekulargewicht: 103.17

Ref: 02-L14166

(R)-(-)-2-Amino-3-methylbutan-1-ol

CAS: 4276-09-9

(R)-(-)-2-Amino-3-methylbutan-1-ol

Formel: C₅H₁₃NO

Reinheit: 97%

Farbe und Form: Colourless Solid-Crystals

Molekulargewicht: 103.16281

Ref: 54-OR5885

D-Valinol

CAS: 4276-09-9

Formel: C₅H₁₃NO

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 103.1628

Ref: IN-DA00I896

D-(-)-Valinol ((R)-(-)-2-Amino-3-methyl-1-butanol)

CAS: 4276-09-9

Formel: C₅H₁₃NO

Molekulargewicht: 103.17

Ref: 7W-GE5589

D-Valinol

CAS: 4276-09-9

D-Valinol is a synthetic compound that contains a chiral alcohol group. It is an ester hydrochloride salt of D-valinol and has been shown to be clinically effective in treating chronic lymphocytic leukemia (CLL). This drug is a potent inhibitor of the bcr-abl kinase, which is involved in the regulation of protein synthesis. D-Valinol binds to the kinase domain of this enzyme and inhibits its activity by preventing it from transferring phosphate groups from ATP to tyrosine residues on proteins. D-Valinol also inhibits chloride channels, which are required for cell survival.

Formel: C₅H₁₃NO

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 103.16 g/mol

Ref: 3D-FV36829

d-Valinol

CAS: 4276-09-9

Formel: C₅H₁₃NO

Reinheit: 97%

Farbe und Form: Solid, Low Melting Solid

Molekulargewicht: 103.165

Ref: 10-F045548

D-Valinol

Kontrolliertes Produkt

CAS: 4276-09-9

Applications D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer's disease.
References Radl, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2015, ahead of print); Fukunaga, K., et al.: Bioorg. Med. Chem. Lett., 25, 1086 (2015)

Formel: C₅H₁₃NO

Farbe und Form: Neat

Molekulargewicht: 103.16

Ref: TR-V094355

D-Valinol

CAS: 4276-09-9

D-Valinol is a fine chemical that has been used as an intermediate in the synthesis of other chemicals. It is also a versatile building block for organic reactions, such as condensation reactions. D-Valinol is a white solid and has CAS No. 4276-09-9. It can be used as a reagent or catalyst in the synthesis of pharmaceuticals, agrochemicals, and other speciality chemicals. D-Valinol is also useful as an intermediate in the production of high quality research chemicals and speciality chemicals.

Formel: C₅H₁₃NO

Reinheit: Min. 98.0 Area-%

Molekulargewicht: 103.1 g/mol

Ref: 3D-Q-102724