CAS 51166-71-3

Di-O-methyl-β-cyclodextrin

Beschreibung:

Di-O-methyl-β-cyclodextrin ist ein modifiziertes Derivat von β-Cyclodextrin, das ein zyklisches Oligosaccharid ist, das aus sieben Glukoseeinheiten besteht. Diese Verbindung weist zwei Methoxygruppen auf, die an den Hydroxylpositionen der Glukoseeinheiten angebracht sind, was ihre Löslichkeit in organischen Lösungsmitteln erhöht und ihre Fähigkeit verbessert, Einschlusskomplexe mit verschiedenen Gastmolekülen zu bilden. Di-O-methyl-β-cyclodextrin zeigt Eigenschaften wie eine erhöhte Lipophilie im Vergleich zu nativer β-Cyclodextrin, was es in pharmazeutischen Anwendungen für die Arzneimittelabgabe und -stabilisierung nützlich macht. Es hat ein relativ niedriges Toxizitätsprofil und wird allgemein als sicher für die Verwendung in Lebensmittel- und pharmazeutischen Formulierungen anerkannt. Die Fähigkeit der Verbindung, hydrophobe Verbindungen einzuschließen, ermöglicht eine verbesserte Bioverfügbarkeit und kontrollierte Freisetzung aktiver Inhaltsstoffe. Darüber hinaus kann es die Stabilität empfindlicher Verbindungen gegen Abbau erhöhen. Seine Anwendungen erstrecken sich auf Bereiche wie Kosmetik, Lebensmittelwissenschaft und Umweltremediation, wo es bei der Löslichkeit und Abgabe verschiedener Substanzen helfen kann.

Formel: C₅₆H₉₈O₃₅

InChl: InChI=1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1

InChI Key: InChIKey=QGKBSGBYSPTPKJ-UZMKXNTCSA-N

SMILES: C(OC)[C@@H]1[C@@]2([C@H](O)[C@@H](OC)[C@](O1)(O[C@@]3([C@@H](COC)O[C@@]([C@H](OC)[C@H]3O)(O[C@@]4([C@@H](COC)O[C@@]([C@H](OC)[C@H]4O)(O[C@@]5([C@@H](COC)O[C@](O[C@]6([C@H](O)[C@@H](OC)[C@@](O[C@]7([C@H](O)[C@@H](OC)[C@@](O[C@]8([C@H](O)[C@@H](OC)[C@@](O2)(O[C@@H]8COC)[H])[H])(O[C@@H]7COC)[H])[H])(O[C@@H]6COC)[H])[H])([C@H](OC)[C@H]5O)[H])[H])[H])[H])[H])[H])[H])[H]

Synonyme:

• 2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26.2^28,31]nonatetracontane, β-cyclodextrin deriv.
• 2,6-2-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-methyl-β-cyclodextrin
• 2,6-Dimethyl-β-cyclodextrin
• 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-Tetradeca-O-methyl-β-cyclodextrin
• 2^A,6^A-Di-O-methyl-β-cyclodextrin
• Beta W 7M1.8
• Di-O-methyl-β-cyclodextrin
• Dimeb
• Dimeb 50
• Dimethyl-β-cyclodextrin
• Hepta-(2,6-di-oxy-methyl)-β-cyclodextrin
• Heptakis(2,6-di-O-methyl)-β-cyclodextrin
• Tetradeca-O-methyl-β-cyclodextrin
• Tetradecakis-2,6-O-methylcycloheptaamylose
• β-Cyclodextrin, 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-tetradeca-O-methyl-
• β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-tetradeca-O-methyl-
• 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-Tetradeca-O-methyl-β-cyclodextrin

2,6-Di-O-methyl-beta-cyclodextrin

CAS: 51166-71-3

Formel: C₅₆H₉₈O₃₅

Reinheit: >95.0%(HPLC)

Farbe und Form: White to Light yellow powder to crystal

Molekulargewicht: 1,331.37

Ref: 3B-D5992

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

CAS: 51166-71-3

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

Formel: C₅₆H₉₈O₃₅

Reinheit: 95%

Farbe und Form: Solid-Powder

Molekulargewicht: 1331.35631

Ref: 54-BICY1000

Heptakis(2,6-di-O-methyl)-b-cyclodextrin

CAS: 51166-71-3

Formel: C₅₆H₉₈O₃₅

Reinheit: ≥ 98% (2,6-Di-O-methyl-b-CD + other methyl CDs)

Farbe und Form: White to off-white powder

Molekulargewicht: 1331.36

Ref: 7W-GC9584

β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-tetradeca-O-methyl-

CAS: 51166-71-3

Formel: C₅₆H₉₈O₃₅

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 1331.3563

Ref: IN-DA00I95Q

DM-β-CD

CAS: 51166-71-3

DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule composed of seven glucose units, modified with two methyl groups at the 2 and 6 positions. It is commonly utilized as a solubilizer and carrier for poorly soluble drugs in pharmaceutical formulations. Additionally, its ability to form inclusion complexes with various guest molecules—such as aromatic compounds, pesticides, and heavy metals—makes it valuable in analytical chemistry, food science, and environmental remediation.

Formel: C₅₆H₉₈O₃₅

Molekulargewicht: 1331.3563

Ref: TM-TSH-00009

Di-O-methyl-b-cyclodextrin (90%)

Kontrolliertes Produkt

CAS: 51166-71-3

Applications Induces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods
References Krajian, H., et al.: Anal. Bioanal. Chem., 394, 2193 (2009), Perez-Cruz, F., et al.: Bioorg. Med. Chem., 17, 4604 (2009), Motoyama, K., et al.: Biol. Pharm. Bull., 32, 700 (2009), Padula, C., et al.: Int. J. Pharm., 372, 12 (2009), Chen, Z., et al.: J. Pharm. Sci., 98, 229 (2009),

Formel: C₅₆H₉₈O₃₅

Reinheit: 90%

Farbe und Form: Neat

Molekulargewicht: 1331.36

Ref: TR-D470870

2,6-Dimethyl-b-cyclodextrin - Technical

CAS: 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formel: C₅₆H₉₈O₃₅

Reinheit: Min. 98%

Farbe und Form: White Powder

Molekulargewicht: 1,331.36 g/mol

Ref: 3D-OD08100

2,6-Dimethyl-beta-cyclodextrin

CAS: 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formel: C₅₆H₉₈O₃₅

Reinheit: Min. 98%

Farbe und Form: White Powder

Molekulargewicht: 1,331.36 g/mol

Ref: 3D-OD29274

2,6-Di-O-methyl-β-cyclodextrin

CAS: 51166-71-3

2,6-Di-O-methyl-β-cyclodextrin

Formel: C₅₆H₉₈O₃₅

Reinheit: 98%

Molekulargewicht: 1331.36

Ref: IN-DG297838

2,6-DI-O-METHYL-β-CYCLODEXTRIN

CAS: 51166-71-3

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 1331.36499

Ref: 10-F813397