CAS 52299-14-6

Succinyl-L-alanyl-L-alanyl-L-alanin p-nitroanilid

Beschreibung:

Succinyl-L-alanyl-L-alanyl-L-alanin p-nitroanilid ist ein synthetisches Peptidsubstrat, das häufig in biochemischen Assays verwendet wird, insbesondere zur Detektion von proteolytischen Enzymen wie Serinproteasen. Diese Verbindung weist eine Succinylgruppe auf, die ihre Löslichkeit und Stabilität verbessert, sowie eine p-Nitroanilidgruppe, die als chromogenes Indikator dient. Bei der enzymatischen Spaltung führt die Freisetzung von p-Nitroanilin zu einer messbaren Farbänderung, die die Quantifizierung der Enzymaktivität ermöglicht. Die Struktur besteht aus einer Sequenz von Aminosäuren, insbesondere L-Alanin-Resten, die zu ihrer Spezifität und Wechselwirkung mit Zielenzymen beitragen. Die Verbindung ist typischerweise in wässrigen Lösungen löslich und zeigt Stabilität unter Standardlaborbedingungen. Ihre Verwendung in Forschungs- und Diagnostikanwendungen hebt ihre Bedeutung für das Verständnis der Enzymkinetik und der Proteininteraktionen hervor. Wie bei vielen Peptidsubstraten sollte auf die Lagerbedingungen und Handhabung geachtet werden, um ihre Integrität und Reaktivität zu erhalten.

Formel: C₁₉H₂₅N₅O₈

InChl: InChI=1S/C19H25N5O8/c1-10(20-15(25)8-9-16(26)27)17(28)21-11(2)18(29)22-12(3)19(30)23-13-4-6-14(7-5-13)24(31)32/h4-7,10-12H,8-9H2,1-3H3,(H,20,25)(H,21,28)(H,22,29)(H,23,30)(H,26,27)/t10-,11-,12-/m0/s1

InChI Key: InChIKey=GVUGADOWXGKRAE-SRVKXCTJSA-N

SMILES: N(C([C@@H](NC([C@@H](NC([C@@H](NC(CCC(O)=O)=O)C)=O)C)=O)C)=O)C1=CC=C(N(=O)=O)C=C1

Synonyme:

• 3-Carboxypropionyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
• 43: PN: CN101457218 PAGE: 2 claimed protein
• <span class="text-smallcaps">L</smallcap>-Alaninamide, N-(3-carboxy-1-oxopropyl)-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanyl-N-(4-nitrophenyl)-
• Chromozym ELA
• N-(3-Carboxy-1-oxopropyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-N-(4-nitrophenyl)-<smallcap>L</span>-alaninamide
• N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-L-alaninamide
• N-SUCCINYL-(L-ALA)3-p-NITROANILIDE **03-32-0009**
• N-Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
• N-Succinyl-Ala-Ala-Ala-p-nitroanilide
• Suc-Ala-Ala-Ala-pNA
• Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine 4-nitroanilide
• Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
• Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanyl p-nitroanilide
• Succinyl-<span class="text-smallcaps">L</span>-trialanine p-nitroanilide
• N-Succinyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide
• 3-Carboxypropionyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide
• L-Alaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-
• Succinyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide

Suc-Ala-Ala-Ala-pNA

CAS: 52299-14-6

Suc-AAA-pNA, a readily soluble and sensitive substrate for human and rat neutrophil and porcine pancreatic elastases. The trialanine substrate is also hydrolyzed by proteinase K, subtilisins and thermitase as well as by astacin, a crayfish zinc-endopeptidase.

Formel: C₁₉H₂₅N₅O₈

Reinheit: > 99%

Farbe und Form: Light Yellow

Molekulargewicht: 451.44

Ref: 01-4000902

SUC-ALA-ALA-ALA-PNA

CAS: 52299-14-6

Formel: C₁₉H₂₅N₅O₈

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 451.4305

Ref: IN-DA00D8ZJ

Suc-AAA-pNA

CAS: 52299-14-6

Suc-AAA-pNA is a synthetic peptide substrate commonly used for protease activity assays and widely applied in biochemical experiments.

Formel: C₁₉H₂₅N₅O₈

Reinheit: 99.75%

Farbe und Form: Solid

Molekulargewicht: 451.43

Ref: TM-T205938

N-Succinyl-Ala-Ala-Ala-p-Nitroanilide

CAS: 52299-14-6

N-Succinyl-Ala-Ala-Ala-p-Nitroanilide

Reinheit: 98%

Molekulargewicht: 451.43g/mol

Ref: 54-OR1014482

Chromozym ELA

CAS: 52299-14-6

Formel: C₁₉H₂₅N₅O₈

Molekulargewicht: 451.44

Ref: 4Z-A-248084

N-Succinyl-L-alanyl-L-alanyl-L-alanine 4-nitroanilide

CAS: 52299-14-6

N-Succinyl-L-alanyl-L-alanyl-L-alanine 4 nitroanilide is a synthetic substrate that has been shown to have proteolytic activity against dextran sulfate, collagen, and sephadex g-100. It also has insecticidal activity in that it inhibits the development of larvae of the insect Drosophila melanogaster. NSLAAALAALAAN can be used as a chemotactic agent for tissue culture cells. This synthetic substrate was also found to have antiinflammatory properties and may be useful in treating chronic bronchitis or other metabolic disorders.

Formel: C₁₉H₂₅N₅O₈

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 451.43 g/mol

Ref: 3D-FS46953

Suc-Ala-Ala-Ala-pNA

CAS: 52299-14-6

Suc-Ala-Ala-Ala-pNA is a protease inhibitor that is used in the treatment of metabolic disorders. It has been shown to have neurotrophic effects, which may be due to its ability to inhibit the activity of proteases, such as cathepsin B and proteinase 3. Suc-Ala-Ala-Ala-pNA has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the activity of proinflammatory cytokines such as interleukin 1β, tumor necrosis factor α, and prostaglandin E2. Suc-Ala-Ala-Ala-pNA has long term efficacy in treating neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Formel: C₁₉H₂₅N₅O₈

Reinheit: Min. 95%

Molekulargewicht: 451.43 g/mol

Ref: 3D-SAA-3071

Suc-Ala-Ala-Ala-pNA

Kontrolliertes Produkt

CAS: 52299-14-6

Formel: C₁₉H₂₅N₅O₈

Farbe und Form: Neat

Molekulargewicht: 451.43

Ref: TR-S224165

Suc-Ala-Ala-Ala-pNA

CAS: 52299-14-6

Suc-Ala-Ala-Ala-pNA is a peptide that binds to the acetylcholine receptor and activates it. This peptide has been shown to have potential as a research tool for studying the pharmacology of acetylcholine receptors in vitro. It has also been used as an inhibitor of neuronal ion channels, such as potassium channels, that are involved in the transmission of nerve impulses. Suc-Ala-Ala-Ala-pNA is not suitable for use in humans because it would be broken down by proteases before it could reach its target, but this peptide has applications in cell biology and neuroscience.

Formel: C₁₉H₂₅N₅O₈

Reinheit: Min. 95%

Molekulargewicht: 451.43 g/mol

Ref: 3D-SAA-3071-V