CAS 59259-75-5

Formel: C18H23ClN2O

InChl: InChI=1S/C18H22N2O.ClH/c1-19-11-4-12-20-17-6-3-2-5-14(17)7-8-15-13-16(21)9-10-18(15)20;/h2-3,5-6,9-10,13,19,21H,4,7-8,11-12H2,1H3;1H

InChI Key: LCRZCUOKZSTKBD-UHFFFAOYSA-N

SMILES: CNCCCN1C2=C(CCC3=CC=CC=C31)C=C(C=C2)O.Cl

2-Hydroxydesipramine Dihydrochloride

Kontrolliertes Produkt

CAS: 59259-75-5

Applications 2-Hydroxydesipramine Dihydrochloride is a metabolite of Desipramine (D290050), a tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References De Jongh, G.D., et al.: Drug Metab. Dispos., 2, 48 (1981); Suckow, R.F., et al.: J. Pharm. Sci., 73, 1745 (1984); Fraser, A.D., et al.: J. Anal. Toxicol., 11,168 (1987); Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981); Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998); Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999); Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003)

Formel: C₁₈H₂₂N₂O·2HCl

Farbe und Form: Neat

Molekulargewicht: 355.3

Ref: TR-H936505