CAS 60976-49-0

Geraniin

Beschreibung:

Geraniin ist eine natürlich vorkommende polyphenolische Verbindung, die hauptsächlich in verschiedenen Pflanzen, insbesondere in der Familie der Geraniaceae, vorkommt. Sie ist bekannt für ihre potenziellen gesundheitlichen Vorteile, einschließlich antioxidativer, entzündungshemmender und antimikrobieller Eigenschaften. Geraniin ist eine Art von Ellagitannin, was bedeutet, dass es aus der Kondensation von Ellagsäure und Glukose abgeleitet ist. Diese Verbindung wird oft für ihre Rolle in der traditionellen Medizin und ihre potenziellen Anwendungen in Nutraceuticals und Pharmazeutika untersucht. Geraniin zeigt Löslichkeit in organischen Lösungsmitteln und hat eine relativ komplexe Struktur, die zu ihrer biologischen Aktivität beiträgt. Zu ihren chemischen Eigenschaften gehört die Fähigkeit, Komplexe mit Metallionen zu bilden und mit verschiedenen biologischen Makromolekülen zu interagieren, was sie zu einem interessanten Thema sowohl in der medizinischen Chemie als auch in der Forschung zu Naturstoffen macht. Darüber hinaus werden laufende Studien durchgeführt, um ihre Auswirkungen auf verschiedene Gesundheitszustände, einschließlich Krebs und Stoffwechselstörungen, zu untersuchen, was ihre Bedeutung im Bereich der Naturstoffchemie unterstreicht.

Formel: C₆H₁₂O₆

InChl: InChI=1/C41H28O27/c42-13-1-8(2-14(43)24(13)48)34(54)67-39-33-32-30(64-38(58)12-6-19(47)41(61)40(59,60)23(12)22-11(37(57)66-33)5-17(46)27(51)31(22)68-41)18(63-39)7-62-35(55)9-3-15(44)25(49)28(52)20(9)21-10(36(56)65-32)4-16(45)26(50)29(21)53/h1-6,18,23,30,32-33,39,42-46,48-53,59-61H,7H2

InChI Key: InChIKey=JQQBXPCJFAKSPG-UHFFFAOYSA-N

SMILES: OC1(O)C2C=3C=4OC1(O)C(=O)C=C2C(=O)OC5C6C(OC(=O)C3C=C(O)C4O)C(OC(=O)C7=CC(O)=C(O)C(O)=C7)OC5COC(=O)C=8C(C=9C(C(=O)O6)=CC(O)=C(O)C9O)=C(O)C(O)=C(O)C8

Synonyme:

• (1R,7R,8S,26R,28S,29R,38R)-1,13,14,15,18,19,20,34,35,39,39-Undecahydroxy-2,5,10,23,31-pentaoxo-6,9,24,27,30,40-hexaoxaoctacyclo[34.3.1.0~4,38~.0~7,26~.0~8,29~.0~11,16~.0~17,22~.0~32,37~]tetraconta-3,11,13,15,17,19,21,32,34,36-decaen-28-yl 3,4,5-trihydroxybenzoate
• (26bR)-2,3,11,12,13,14,15,16,26,26,26a-undecahydroxy-5,9,18,23,25-pentaoxo-5,7a,9,18,20,21,21a,23,25,26,26a,26b-dodecahydro-7H-21,7-(epoxymethano)-1,6,8,19,22-pentaoxadibenzo[5',6':7',8']cyclododeca[1',2':7,8]cycloundeca[1,2,3,4-def]fluoren-28-yl 3,4,5-tr
• (26bR)-2,3,11,12,13,14,15,16,26,26,26a-undecahydroxy-5,9,18,23,25-pentaoxo-5,7a,9,18,20,21,21a,23,25,26,26a,26b-dodecahydro-7H-21,7-(epoxymethano)-1,6,8,19,22-pentaoxadibenzo[5',6':7',8']cyclododeca[1',2':7,8]cycloundeca[1,2,3,4-def]fluoren-28-yl 3,4,5-trihydroxybenzoate
• (3R,4aR)-3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-pentaoxo-2,3,4,4a,9,11a,13,22,24,25,25a,27-dodecahydro-11H-3,5-epoxy-25,11-(epoxymethano)dibenzo[h,j]dibenzo[7,8:9,10][1,5]dioxacycloundecino[3,2-b][1,6]dioxacyclododecin-29-yl 3,4,5-trihydro
• (3R,4aR,11R,11aS,25R,25aR,29R)-3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-pentaoxo-2,3,4,4a,9,11a,13,22,24,25,25a,27-dodecahydro-11H-3,5-epoxy-25,11-(epoxymethano)dibenzo[h,j]dibenzo[7,8:9,10][1,5]dioxacycloundecino[3,2-b][1,6]dioxacyclododeci
• (3R,4aR,11R,11aS,25R,25aR,29S)-3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-pentaoxo-2,3,4,4a,9,11a,13,22,24,25,25a,27-dodecahydro-11H-3,5-epoxy-25,11-(epoxymethano)dibenzo[h,j]dibenzo[7,8:9,10][1,5]dioxacycloundecino[3,2-b][1,6]dioxacyclododeci
• Geraniin
• Geraniin (b form)
• NSC 359346
• benzoic acid, 3,4,5-trihydroxy-, (26bR)-5,7a,9,18,20,21,21a,23,25,26,26a,26b-dodecahydro-2,3,11,12,13,14,15,16,26,26,26a-undecahydroxy-5,9,18,23,25-pentaoxo-21,7-(epoxymethano)-7H-1,6,8,19,22-pentaoxadibenzo[5',6':7',8']cyclododeca[1',2':7,8]cycloundeca[1,2,3,4-def]fluoren-28-yl ester
• benzoic acid, 3,4,5-trihydroxy-, (3R,4aR,11R,11aS,25R,25aR,29S)-2,3,4,4a,9,11a,13,22,24,25,25a,27-dodecahydro-3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-pentaoxo-3,5-epoxy-25,11-(epoxymethano)-11H-dibenzo[h,j]dibenzo[7,8:9,10][1,5]dioxacycloundecino[3,2-b][1,6]dioxacyclododecin-29-yl ester
• β-<span class="text-smallcaps">D</span>-Glucopyranose, cyclic 2→7:4→5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), stereoisomer
• β-D-Glucopyranose, cyclic 2→7:4→5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), stereoisomer
• 3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-pentaoxo-2,3,4,4a,9,11a,13,22,24,25,25a,27-dodecahydro-11H-3,5-epoxy-25,11-(epoxymethano)dibenzo[h,j]dibenzo[7,8:9,10][1,5]dioxacycloundecino[3,2-b][1,6]dioxacyclododecin-29-yl 3,4,5-trihydroxybenzoat
• 5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-Methano-2H-1-benzoxocin-5,7-dicarboxylate)cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate)1-(3,4,5-trihydroxybenzoate), stereoisoMer
• β-D-Glucopyranose, cyclic 2→7:4→5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), stereoisomer
• B-D-GLUCOPYRANOSE
• b-D-Glucopyranose, cyclic 2&reg
• 7:4&reg
• beta-D-Glucopyranose cyclic 2-7:4-5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate) stereoisomer

Geraniin

CAS: 60976-49-0

Formel: C₄₁H₂₈O₂₇

Molekulargewicht: 952.65

Ref: 7W-GY2028

Geraniin

CAS: 60976-49-0

Geraniin

Formel: C₄₁H₂₈O₂₇

Reinheit: ≥95%

Molekulargewicht: 952.64

Ref: 54-BUP07869

Geraniin

CAS: 60976-49-0

Formel: C₄₁H₂₈O₂₇

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 952.6448

Ref: IN-DA00E9DE

Geraniin (Standard)

CAS: 60976-49-0

Geraniin (Standard) is a reference standard for research and analysis in studies involving Geraniin. 1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation in vitro and suppresses Ti particle-induced osteolysis in vivo, is a potential natural compound for the treatment of wear particle induced osteolysis in prostheses failure. 4. Geraniin has anti-oxidant activity, induces Nrf2-mediated expression of antioxidant enzymes HO-1 and NQO1, presumably via PI3K/AKT and ERK1/2 signaling pathways, thereby protecting cells from H2O2-induced oxidative cell death. 5. Geraniin presents radioprotective effects by regulating DNA damage on splenocytes, exerting immunostimulatory capacities and inhibiting apoptosis of radiosensitive immune cells and jejunal crypt cells.

Formel: C₄₁H₂₈O₂₇

Molekulargewicht: 952.6448

Ref: TM-TMSM-2525

Geraniin

CAS: 60976-49-0

Formel: C₄₁H₂₈O₂₇

Reinheit: 95%~99%

Molekulargewicht: 952.648

Ref: BP-BP0639

Geraniin

CAS: 60976-49-0

Geraniin combats osteoporosis, cancer, and oxidative cell death, enhances radioprotection, and may treat prostheses wear.

Formel: C₄₁H₂₈O₂₇

Reinheit: 97.86% - 99.49%

Farbe und Form: Solid

Molekulargewicht: 952.6448

Ref: TM-T6S2099

Geraniin

CAS: 60976-49-0

Natural glycoside

Formel: C₄₁H₂₈O₂₇

Reinheit: ≥ 90.0 % (HPLC)

Farbe und Form: Powder

Molekulargewicht: 952.66

Ref: 5G-80994

Geraniin

Kontrolliertes Produkt

CAS: 60976-49-0

Geraniin is a natural compound that has been shown to have potent anti-inflammatory and antimicrobial effects. Geraniin has been shown to inhibit the matrix metalloproteinase (MMP) activity of collagenase in vitro, suggesting that it may be a potential treatment for diseases caused by MMPs such as arthritis. Geraniin also inhibits the production of cytokines such as growth factor-β1 and interleukin-1β. It was also found to control the expression of c-Jun in both human cells and a model system. The administration of geraniin showed no toxicity in rats at doses up to 1,000 mg/kg body weight.

Formel: C₄₁H₂₈O₂₇

Reinheit: Min. 98 Area-%

Farbe und Form: Powder

Molekulargewicht: 952.64 g/mol

Ref: 3D-MG74023

Geraniin

CAS: 60976-49-0

Formel: C₄₁H₂₈O₂₇

Molekulargewicht: 952.6

Ref: BE-RMT13393

Geraniin

CAS: 60976-49-0

(57R,58S,510R,511R,519S)-14,15,16,24,25,26,52,53,516,517,517-Undecahydroxy-55,513,515,3,8-pentaoxo-55,57,58,510,511,513,515,516,517,517a-decahydro-4,7-dioxa-5(19,10)-1,16-epoxy-7,11-methanodibenzo[i,k][1,4,7]trioxacyclotridecina-1,2(1,2)-dibenzenacyclooctaphane-58-yl 3,4,5-trihydroxybenzoate

Formel: C₄₁H₂₈O₂₇

Reinheit: 98%

Molekulargewicht: 952.64

Ref: IN-DG115243