CAS 84094-94-0

Formel: C12H14BrN5O3

InChl: InChI=1S/C11H10BrN5O2.CH4O/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6;1-2/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19);2H,1H3/b7-4-;

InChI Key: HRCPXWHLWFTZJA-ZULQGGHCSA-N

SMILES: CO.C\1CNC(=O)C2=C(/C1=C\3/C(=O)NC(=N3)N)C=C(N2)Br

Hymenialdisine Methanoate

Kontrolliertes Produkt

CAS: 82005-12-7, 84094-94-0

Applications A potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. A marine sponge alkaloid, a natural product.
References Cheetham, G., et al.: J. Biol. Chem., 277, 42419 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Sharma, V., et al.: Bioorg. Med. Chem. Lett., 14, 4319 (2004), Anamika, et al.: Proteins, 58, 180 (2005), Birault, V., et al.: Curr. Med. Chem., 13, 1735 (2006),

Formel: C₁₁H₁₀BrN₅O₂·x(CH₄O)

Farbe und Form: Neat

Molekulargewicht: 356.18

Ref: TR-H998000