CAS 84573-33-1

(-)-Quinocarcin

Formel: C₁₈H₂₂N₂O₄

InChl: InChI=1S/C18H22N2O4/c1-19-12-7-10(18(21)22)16(19)11-6-9-4-3-5-14(23-2)15(9)13-8-24-17(12)20(11)13/h3-5,10-13,16-17H,6-8H2,1-2H3,(H,21,22)/t10-,11+,12+,13+,16-,17-/m1/s1

InChI Key: InChIKey=VOUMVHRRAVBACH-RXCQEBQVSA-N

SMILES: C(O)(=O)[C@H]1[C@@]2([C@]3(N4[C@](C=5C(C3)=CC=CC5OC)(CO[C@@]4([C@@](N2C)(C1)[H])[H])[H])[H])[H]

Synonyme:

• (-)-Quinocarcin
• (2aR,3S,5R,6R,6aS,11bR)-2a,3,4,5,6,6a,7,11b-Octahydro-11-methoxy-12-methyl-3,6-imino-1H-2-oxa-11c-azanaphth[1,2,3-cd]azulene-5-carboxylic acid
• 3,6-Imino-1H-2-oxa-11c-azanaphth[1,2,3-cd]azulene-5-carboxylic acid, 2a,3,4,5,6,6a,7,11b-octahydro-11-methoxy-12-methyl-, (2aR,3S,5R,6R,6aS,11bR)-
• 3,6-Imino-1H-2-oxa-11c-azanaphth[1,2,3-cd]azulene-5-carboxylic acid, 2a,3,4,5,6,6a,7,11b-octahydro-11-methoxy-12-methyl-, [2aR-(2aα,3α,5α,6α,6aα,11bα)]-
• Antibiotic DC 52
• Dc-52

(-)-Quinocarcin

Kontrolliertes Produkt

CAS: 84573-33-1

Applications (-)-Quinocarcin are potent antitumor antibiotics that plays a key role in the construction of tetracyclic THIQ-pyrrolidine core scaffold.
References Hiratsuka, T., et al.: Chem. Biol., 20, 1523-1535 (2013)

Formel: C₁₈H₂₂N₂O₄

Farbe und Form: Neat

Molekulargewicht: 330.378

Ref: TR-Q696550

Quinocarcin

CAS: 84573-33-1

Quinocarcin is an antitumor antibiotic, which is a potent chemical compound derived from the bacterium Streptomyces. This compound exhibits its mode of action through interaction with DNA, where it induces DNA cross-linking and inhibits DNA replication, ultimately leading to cell death. The mechanism makes it particularly effective as a cytotoxic agent against rapidly dividing cancer cells.

Formel: C₁₈H₂₂N₂O₄

Reinheit: Min. 95%

Molekulargewicht: 330.4 g/mol

Ref: 3D-JDA57333

Quinocarcin

CAS: 84573-33-1

Quinocarcin (DC-52) is a potent antitumor antibiotic. It inhibits the synthesis of DNA, RNA, and proteins in Bacillus subtilis.

Formel: C₁₈H₂₂N₂O₄

Farbe und Form: Solid

Molekulargewicht: 330.38

Ref: TM-T210315