CAS 847926-88-9

Formel: C14H12N2O

InChl: InChI=1S/C14H12N2O/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)16-14(13)17/h1-8,13H,15H2,(H,16,17)/t13-/m0/s1

InChI Key: NIDGAHURPWFSKR-ZDUSSCGKSA-N

SMILES: C1=CC=C2C(=C1)[C@@H](C(=O)NC3=CC=CC=C23)N

(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

Kontrolliertes Produkt

CAS: 847926-88-9

Applications (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one a building block for γ-secretase inhibitors for treatment of Alzheimer's disease (1,2). Several γ-secretase inhibitors have been described that contain this compound.
References (1) Beher, D., et al.: Exp. Opin. Investig. Drugs, 14, 1385 (2005) (2) Fauq, A., et al.: Bioorg. Med. Chem. Lett., 17, 6392 (2007)

Formel: C₁₄H₁₂N₂O

Farbe und Form: Neat

Molekulargewicht: 224.26

Ref: TR-A604380

(S)-7-Amino-5H,7H-dibenzo[B,D]azepin-6-one

CAS: 847926-88-9

7-Amino-5H,7H-dibenzo[b,D]azepin-6-one is an enantiomer of 7-amino-5H,7H-dibenzo[b,d]azepin-6(10H)one. It is a chiral organic compound that can be synthesized by the epimerization of 2-(2′hydroxyphenyl)ethanol with sodium methoxide in methanol. This compound can also be synthesized by a sequence of reactions including racemization and enantioselective synthesis.

Formel: C₁₄H₁₂N₂O

Reinheit: Min. 95%

Molekulargewicht: 224.26 g/mol

Ref: 3D-XIB92688