CAS 88058-72-4

Formel: C16H24ClNO2

InChl: InChI=1S/C16H23NO2.ClH/c1-3-8-17-9-10-19-16-14-11-13(18-2)6-4-12(14)5-7-15(16)17;/h4,6,11,15-16H,3,5,7-10H2,1-2H3;1H/t15-,16-;/m1./s1

InChI Key: KGOJXBIHHNCIDX-QNBGGDODSA-N

SMILES: CCCN1CCO[C@H]2[C@H]1CCC3=C2C=C(C=C3)OC.Cl

Naxagolide-O-methyl Hydrochloride

Kontrolliertes Produkt

CAS: 88058-72-4

Applications Naxagolide-O-methyl Hydrochloride is an intermediate in the synthesis of Naxagolide Hydrochloride (N379800), which is a dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug.
References Fujita, N., et al.: Brain Res., 333, 231 (1985); Weiss, F., et al.: Eur. J, Pharmacol., 337, 219 (1997); Wilson, A., et al.: J. Med. Chem., 48, 4153 (2005); Ginovart, N., et al.: J. Neurochem., 97, 1089 (2006); Willeit, M., et al.: Biol. Psychiatry, 59, 389 (2006)

Formel: C₁₆H₂₃NO₂·HCl

Farbe und Form: Neat

Molekulargewicht: 297.82

Ref: TR-N378805