CAS 9011-18-1

Natriumdextransulfat

Beschreibung:

Natriumdextransulfat ist ein sulfatierter Polysaccharid, das aus Dextrin, einem komplexen verzweigten Glucan, gewonnen wird. Es zeichnet sich durch sein hohes Molekulargewicht aus und wird typischerweise als Antikoagulans und in verschiedenen biomedizinischen Anwendungen verwendet. Die Substanz erscheint als weißes bis off-white Pulver und ist in Wasser löslich, wobei sie eine viskose Lösung bildet. Natriumdextransulfat weist eine negative Ladung aufgrund der Sulfatgruppen auf, was zu seiner Fähigkeit beiträgt, mit Proteinen und anderen Biomolekülen zu interagieren, was es nützlich in Arzneimittellieferungssystemen und als Stabilisator in verschiedenen Formulierungen macht. Darüber hinaus wurde es auf seine potenziellen therapeutischen Wirkungen, einschließlich antiviraler und entzündungshemmender Eigenschaften, untersucht. Sein Sicherheitsprofil ist im Allgemeinen günstig, kann jedoch bei einigen Personen, insbesondere in hohen Konzentrationen, unerwünschte Reaktionen hervorrufen. Wie bei jeder chemischen Substanz sollten angemessene Handhabungs- und Anwendungshinweise befolgt werden, um Sicherheit und Wirksamkeit in ihren Anwendungen zu gewährleisten.

Formel: H₂O₄S·xNa·xUnspecified

Synonyme:

• Asuro
• Colyonal
• Dexnon
• Dextralip 15
• Dextran Sulfate Sodium
• Dextran sodium sulfate
• Dextran sulfate sodium salt
• Dextran sulfuric acid ester sodium salt
• Dextran, hydrogen sulfate, sodium salt
• Dextransulfate sodium sulfur
• Dextrarine
• Dexulate
• MDS (polysaccharide)
• MDS-Kowa A

Dextran sulfate sodium, MW 100,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Farbe und Form: Powder

Ref: 3D-YD59549

Dextran sulfate sodium salt - MW 9,000-11,000 - from Leuconostoc spp

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Reinheit: Min. 95%

Farbe und Form: Powder

Ref: 3D-YD45147

Dextran sulfate sodium, MW 20,000

CAS: 9011-18-1

Sodium carboxymethyl dextran (CM-dextran) is a white, odourless and tasteless powder, which is freely soluble in water or electrolyte solutions. The product has a pronounced polyanionic character, due to the high degree of carboxyl substitution.  Applications that have been described for CM-dextran include carriers of paramagnetic contrast agents, preparation of conjugates of pharmacologically active compounds and CM-dextrans in biosensors.  A number of other uses in cosmetics, agriculture, foods, paints and textiles have been the subject of patent applications.

Farbe und Form: Powder

Ref: 3D-YD31803

Dextran sulfate sodium salt - MW 500,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Formel: C₉H₁₁NO₂

Reinheit: Min. 95%

Farbe und Form: White Powder

Ref: 3D-YD32562

Dextran sulfate sodium salt (MW 5000)

CAS: 9011-18-1

Reinheit: 98%

Ref: 10-F554564

Dextran sulfate sodium - MW 5,000-8,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Formel: (C₆H₇Na₃O₁₄S₃)n

Reinheit: Min. 95%

Farbe und Form: Powder

Ref: 3D-YD31801

Dextran Sulphate Sodium Salt 30-50(DSS 35-50) ex. Leuconostoc Sp.Colitis Grade for molecular biology

CAS: 9011-18-1

Farbe und Form: White to off-white, Powder, Clear, Colourless to pale yellow

Molekulargewicht: made from Dextran 35 - 50 KDa

Ref: SR-76203

Dextran Sulphate Sodium Salt 500 (DSS 500) ex. Leuconostoc Sp. for molecular biology

CAS: 9011-18-1

Farbe und Form: White to pale yellow, Powder, Clear

Molekulargewicht: made from Dextran 500 KDa

Ref: SR-99629

Dextran sulfate sodium - MW 3000-6000

CAS: 9011-18-1

Dextran sulfate sodium is a complex carbohydrate that consists of a linear chain of many glucose molecules. It is often used as a gel to protect the bowel during radiation therapy and in the treatment of severe burns. Dextran sulfate sodium can be modified with methylation, click modification, fluorination, saccharide, or glycosylation. Dextran sulfate sodium also has many applications in biochemistry and medicine such as being used as an osmotic agent in cell culture media, after being glycosylated it can be used to treat inflammatory bowel disease. This product is custom synthesized by our company and is available in various sizes from MW 3000-6000.

Reinheit: Min. 95%

Farbe und Form: Powder

Ref: 3D-YD176024

Dextran sulfate sodium salt - MW 150,000

CAS: 9011-18-1

Induces ulceration; used to model inflammatory bowel disease

Reinheit: Min. 95%

Farbe und Form: Powder

Ref: 3D-OD157161