CAS 9073-60-3

β-Lactamase

Beschreibung:

β-Lactamase ist ein Enzym, das eine entscheidende Rolle bei der Antibiotikaresistenz spielt, insbesondere gegen β-Lactam-Antibiotika wie Penicilline und Cephalosporine. Es wird von verschiedenen Bakterien produziert, einschließlich sowohl grampositiver als auch gramnegativer Arten. Die Hauptfunktion von β-Lactamase besteht darin, den β-Lactam-Ring dieser Antibiotika zu hydrolysieren, wodurch sie unwirksam werden und Bakterien in der Lage sind, in Anwesenheit dieser Medikamente zu überleben. Das Enzym weist eine Reihe von Eigenschaften auf, einschließlich seiner Fähigkeit, je nach Bakterienstamm und Art des β-Lactam-Antibiotikums in Spezifität und Aktivität zu variieren. β-Lactamases können in verschiedene Gruppen eingeteilt werden, basierend auf ihrer molekularen Struktur und ihrem Wirkmechanismus, einschließlich Serin-β-Lactamases und Metallo-β-Lactamases. Das Vorhandensein von β-Lactamase-Genen in bakteriellen Populationen ist ein bedeutendes Anliegen in klinischen Umgebungen, da es zum wachsenden Problem der Antibiotikaresistenz beiträgt, was die Behandlung von Infektionen erschwert. Das Verständnis der Mechanismen und Eigenschaften von β-Lactamases ist entscheidend für die Entwicklung neuer Strategien zur Bekämpfung von antibiotikaresistenten Infektionen.

Formel: Unspecified

Synonyme:

• 3: PN: WO2019216248 SEQID: 10 claimed DNA
• Carbapenamase
• Carbapenem hydrolase
• Carbapenem-hydrolyzing β-lactamase
• Carbapenemase
• Carbapenemase 1
• Cefinase
• Cefotaximase
• Ceftazidimase
• Ceftazimidase
• Cefuroximase
• Cephalosporinase
• Cephamycinase
• Cloxacilanase
• Difco Penase
• Difco Penase Concentrate
• E.C. 3.5.2.6
• E.C. 3.5.2.8
• Imipenem-hydrolyzing β-lactamase
• Imipenemase
• Lactamasa, Β-
• Lactamase
• Metallo-β-lactamase
• Metallo-β-lactamases
• Neutrapen
• Oxacillinase
• Oxyiminocephalosporinase
• Penase
• Penicilloyl serine transferase
• Proteins, gene blaZ
• β-Lactamase
• β-Lactamase II
• EC 3.5.2.6
• b-Lactamase, Bacillus cereus 569/H9
• CENTA B-LACTAMASE SUBSTRATE

LacBuster™-P bulk (β-lactamase)

CAS: 9073-60-3

Beta-lactamase enzyme targeting beta-lactam antibiotics

Ref: 3D-EBL040.5

LacBuster™ TSA broad range β-lactamase settle plates, 10 plates per pack, barcoded

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL065

LacBuster™ TSA broad range β-lactamase contact plates, 10 plates per pack, barcoded

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL066

LacBuster™ TSA broad range β-lactamase settle plates, 10 plates per pack, barcoded

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL063

LacBuster™ TSA broad range β-lactamase contact plates, 10 plates per pack, barcoded

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL064

LacBuster™-S 2000 (β-lactamase)

CAS: 9073-60-3

LacBuster™-S 2000 is an enzyme preparation, specifically a beta-lactamase, which is derived from bacterial sources known for their capacity to degrade beta-lactam antibiotics. Through hydrolytic cleavage of the beta-lactam ring, this enzyme neutralizes the efficacy of beta-lactam antibiotics, thereby rendering them inactive.

Ref: 3D-EBL023.2

LacBuster™-S 1000 (β-lactamase)

CAS: 9073-60-3

LacBuster™-S 1000 is an enzymatic product derived from microbial sources, specifically engineered for precision and efficiency. It is a beta-lactamase, which catalyzes the hydrolysis of the beta-lactam ring found in beta-lactam antibiotics such as penicillins and cephalosporins, rendering them inactive. The enzyme achieves this by breaking the amide bond within the beta-lactam ring, a critical structural component necessary for antibiotic activity.

Ref: 3D-EBL022.2

LacBuster™-S 5000 (β-lactamase)

CAS: 9073-60-3

LacBuster™-S 5000 is an enzymatic product, specifically a beta-lactamase, which originates from microbial sources known for their ability to produce enzymes that break down antibiotics. This product functions by hydrolyzing the beta-lactam ring of relevant antibiotics, thereby neutralizing their antibacterial activity.

Ref: 3D-EBL025.2

LacBuster™-S 50 (β-lactamase)

CAS: 9073-60-3

LacBuster™-S 50 is a beta-lactamase formulation, which is an enzyme of microbial origin with the ability to hydrolyze beta-lactam antibiotics. This enzymatic product is derived from specific bacterial species known for their resistance mechanisms, providing a robust capability to deactivate compounds such as penicillins and cephalosporins. Its mode of action involves the cleavage of the beta-lactam ring, a crucial structural component of these antibiotics, effectively neutralizing their antibacterial properties.

Ref: 3D-EBL021.2

LacBuster™-L concentrate

CAS: 9073-60-3

Beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.

Ref: 3D-EBL019.7

LacBuster™-L 100 (beta-lactamase)

CAS: 9073-60-3

Ready to use beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.beta lactamase I activity - min. 25.0 IU/mLbeta lactamase II activity - min. 10.0 IU/mL

Ref: 3D-EBL014.3

LacBuster™ (b-lactamase) settle plates

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL061

CENTA(TM) β-LACTAMASE SUBSTRATE

CAS: 9073-60-3

Formel: C₂₁H₁₇N₃O₈S₃

Farbe und Form: Solid

Molekulargewicht: 535.5700

Ref: IN-DA00GRR6

LacBuster™ (b-lactamase) contact plates

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL062