CAS: 918504-65-1 - Vemurafenib

Formel: C₂₃H₁₈ClF₂N₃O₃S

InChl: InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28)

InChI Key: InChIKey=GPXBXXGIAQBQNI-UHFFFAOYSA-N

SMILES: O=C(C1=CNC2=NC=C(C=C21)C=3C=CC(Cl)=CC3)C=4C(F)=CC=C(NS(=O)(=O)CCC)C4F

Synonyme:

• 1-Propanesulfonamide, N-[3-[[5-(4-Chlorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]Carbonyl]-2,4-Difluorophenyl]-
• N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide
• N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
• Plx 4032
• Plx-4032 (RG7024)
• Propane-1-sulfonic acid [3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]amide
• Rg 7204
• Ro 51-85426
• Ro 5185426
• Zelboraf

N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide

CAS: 918504-65-1

• Formel: C₂₃H₁₈ClF₂N₃O₃S
• Farbe und Form: Solid
• Molekulargewicht: 489.9221

Vemurafenib

CAS: 918504-65-1

• Formel: C₂₃H₁₈ClF₂N₃O₃S
• Farbe und Form: Off-White Solid
• Molekulargewicht: 489.93

PLX4032

CAS: 918504-65-1

Vemurafenib

CAS: 918504-65-1

Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and …

• Formel: C₂₃H₁₈ClF₂N₃O₃S
• Reinheit: 99.65%
• Farbe und Form: Solid
• Molekulargewicht: 489.92

Vemurafenib

CAS: 918504-65-1

Applications Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation …

• Formel: C₂₃H₁₈ClF₂N₃O₃S
• Farbe und Form: Neat
• Molekulargewicht: 489.92