CAS 931963-55-2

1H-Thiopyrano[4,3-b][1]benzothiophene-3-carboxamide, 6,7,8,9-tetrahydro-N-[3-(3-methyl-1-piperidinyl)propyl]-

Formel: C₂₁H₃₀N₂OS₂

InChl: InChI=1S/C21H30N2OS2/c1-15-6-4-10-23(13-15)11-5-9-22-21(24)20-12-19-17(14-25-20)16-7-2-3-8-18(16)26-19/h12,15H,2-11,13-14H2,1H3,(H,22,24)

InChI Key: KTLYLDMTGYBKTC-UHFFFAOYSA-N

SMILES: CC1CCCN(C1)CCCNC(=O)C2=CC3=C(CS2)C4=C(S3)CCCC4

Synonyme:

• 1H-Thiopyrano[4,3-b][1]benzothiophene-3-carboxamide, 6,7,8,9-tetrahydro-N-[3-(3-methyl-1-piperidinyl)propyl]-
• E722-2648

E722-2648

CAS: 931963-55-2

E722-2648 is a potent inhibitor of the β-catenin/BCL9 complex, specifically preventing its formation and inhibiting Wnt activity. It disrupts cholesterol homeostasis through increased cholesterol esterification and accumulation of lipid droplets. Additionally, E722-2648 exhibits antitumor activity [1].

Formel: C₂₁H₃₀N₂OS₂

Molekulargewicht: 390.61

Ref: TM-T86330