CAS 93957-50-7

(2E)-3-[3-(4-fluorphenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal

Formel: C₂₀H₁₈FNO

InChl: InChI=1S/C20H18FNO/c1-14(2)22-18-7-4-3-6-17(18)20(19(22)8-5-13-23)15-9-11-16(21)12-10-15/h3-14H,1-2H3/b8-5+

InChI Key: InChIKey=DVWHSTKQJBIYCK-VMPITWQZSA-N

SMILES: C(=C/C=O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3

Synonyme:

• (2E)-3-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-2-Propenal
• (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
• (E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-Methylethyl)-1H-Indol-2''-Yl]-2-Propnal
• (E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal
• (E)-3-[3-(4-fluorophenyl)-1-(1-methylethyl)-2-indolyl]propenal
• 2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-
• 2-Propenal,3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (E)-
• Fluvastatin intermediate

(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein

CAS: 93957-50-7

Formel: C₂₀H₁₈FNO

Reinheit: >98.0%(GC)

Farbe und Form: Light orange to Yellow to Green powder to crystal

Molekulargewicht: 307.37

Ref: 3B-F0819

2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-

CAS: 93957-50-7

Formel: C₂₀H₁₈FNO

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 307.3614

Ref: IN-DA003C0F

(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde

CAS: 93957-50-7

(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde

Formel: C₂₀H₁₈FNO

Reinheit: 98%

Molekulargewicht: 307.368

Ref: 54-PC103955

(E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]prop-2-enal

CAS: 93957-50-7

Farbe und Form: Neat

Ref: 86-MM0676.14

(E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal

CAS: 93957-50-7

(E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal is an amoebicidal agent that belongs to the class of indole derivatives. It has been shown to inhibit tumor growth in animal models, and thus may be a potential anti-cancer drug. The activity index of (E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal was significantly lower than those of fenoldopam, a well known antihypertensive agent, for the treatment of liver cancer. The compound also inhibits the growth of bacteria by inhibiting protein synthesis in organisms such as amoeba.

Formel: C₂₀H₁₈FNO

Reinheit: Min. 95%

Farbe und Form: Yellow Powder

Molekulargewicht: 307.36 g/mol

Ref: 3D-FF37514

(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7

Kontrolliertes Produkt

CAS: 93957-50-7

Applications (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7 an isotope labelled reactant used in the synthesis of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor.
References Sacharia, J.R., et. al.: J. Org. Chem., 75, 7514 (2010); Kim, A., Kim, I.S.: Bull. Korean Chem. Soc., 32, 3748 (2011); Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)

Formel: C₂₀D₇H₁₁FNO

Farbe und Form: Neat

Molekulargewicht: 314.405

Ref: TR-F595672

(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde

CAS: 93957-50-7

(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde

Formel: C₂₀H₁₈FNO

Reinheit: 98%

Molekulargewicht: 307.36

Ref: IN-DG23191

(E)-3-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-propenal

CAS: 93957-50-7

Formel: C₂₀H₁₈FNO

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 307.368

Ref: 10-F036562

(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde

Kontrolliertes Produkt

CAS: 93957-50-7

Formel: C₂₀H₁₈FNO

Farbe und Form: Neat

Molekulargewicht: 307.36

Ref: TR-F595670