CAS 944808-88-2

Formel: C18H17ClFN5O2

InChl: InChI=1S/C18H17ClFN5O2/c1-11-21-24-18(26-11)15-4-5-17(23-22-15)25-8-6-13(7-9-25)27-16-10-12(20)2-3-14(16)19/h2-5,10,13H,6-9H2,1H3

InChI Key: WFOFPVXMPTVOTJ-UHFFFAOYSA-N

SMILES: CC1=NN=C(O1)C2=NN=C(C=C2)N3CCC(CC3)OC4=C(C=CC(=C4)F)Cl

CAY10566

CAS: 944808-88-2

CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.

Formel: C₁₈H₁₇ClFN₅O₂

Reinheit: 99.54% - 99.75%

Farbe und Form: Solid

Molekulargewicht: 389.81

Ref: TM-T14878

2-(6-(4-(2-Chloro-5-fluorophenoxy)piperidin-1-yl)pyridazin-3-yl)-5-methyl-1,3,4-oxadiazole

CAS: 944808-88-2

Formel: C₁₈H₁₇ClFN₅O₂

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 389.8113

Ref: IN-DA003OPY

CAY10566

CAS: 944808-88-2

CAY10566

Formel: C₁₈H₁₇ClFN₅O₂

Reinheit: ≥98%

Molekulargewicht: 389.81

Ref: 54-BUP08559

CAY10566

CAS: 944808-88-2

2-(6-(4-(2-Chloro-5-fluorophenoxy)piperidin-1-yl)pyridazin-3-yl)-5-methyl-1,3,4-oxadiazole

Formel: C₁₈H₁₇ClFN₅O₂

Reinheit: 98%

Molekulargewicht: 389.81

Ref: IN-DG379810

CAY 10566

Kontrolliertes Produkt

CAS: 944808-88-2

Applications CAY10566, is a stearoyl-CoA desaturase (SCD) inhibitor.
References Masuda M. et al.: J Lipid Res. 2012 Aug;53(8):1543-52.;

Formel: C₁₈H₁₇ClFN₅O₂

Farbe und Form: Neat

Molekulargewicht: 389.81

Ref: TR-C227125

2-(6-(4-(2-CHLORO-5-FLUOROPHENOXY)PIPERIDIN-1-YL)PYRIDAZIN-3-YL)-5-METHYL-1,3,4-OXADIAZOLE

CAS: 944808-88-2

Reinheit: 98%

Molekulargewicht: 389.8200073

Ref: 10-F813020

CAY10566

CAS: 944808-88-2

CAY10566 is a novel compound that has been shown to induce apoptosis in cells. It binds to the cytosolic protein cytochrome c, which is involved in the mitochondrial electron transport chain. This binding leads to an increase of intracellular levels of hydrogen peroxide and reactive oxygen species (ROS), leading to increased cell apoptosis. CAY10566 also inhibits autophagy, a process that assists in the degradation of cellular components during starvation or other unfavorable conditions. This drug was also found to inhibit cell growth and proliferation by suppressing the MAPK/AMPK pathway, which regulates cellular metabolism and growth.

Formel: C₁₈H₁₇ClFN₅O₂

Reinheit: Min. 95%

Molekulargewicht: 389.82 g/mol

Ref: 3D-UMB80888