CAS 96426-21-0

Glycin-Arginin-Glycin-Asparaginsäure-Serin

Beschreibung:

Die chemische Substanz, die als "Glycin-Arginin-Glycin-Asparaginsäure-Serin" bekannt ist, mit der CAS-Nummer 96426-21-0, ist ein Peptid, das aus vier Aminosäuren besteht: Glycin (Gly), Arginin (Arg), Asparaginsäure (Asp) und Serin (Ser). Dieses Peptid ist bemerkenswert für seine Rolle in biologischen Prozessen, insbesondere bei der Zelladhäsion und Signalübertragung. Die Sequenz der Aminosäuren trägt zu seinen strukturellen und funktionalen Eigenschaften bei, was es in verschiedenen biochemischen Anwendungen, einschließlich der Arzneimittelentwicklung und Gewebeengineering, relevant macht. Glycin-Arginin-Glycin-Asparaginsäure-Serin kann mit spezifischen Rezeptoren oder Proteinen interagieren und das Zellverhalten und die Reaktionen beeinflussen. Seine relativ kleine Größe ermöglicht eine einfache Synthese und Modifikation, was in Forschungs- und Therapiekontexten von Vorteil ist. Darüber hinaus kann das Vorhandensein von geladenen und polaren Seitenketten in den Aminosäuren die Löslichkeit und die Interaktion mit anderen Biomolekülen beeinflussen. Insgesamt dient dieses Peptid als wertvolles Modell zur Untersuchung von Peptidinteraktionen und -funktionen in biologischen Systemen.

Formel: C₁₇H₃₀N₈O₉

InChl: InChI=1/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1

InChI Key: RGNVSYKVCGAEHK-GUBZILKMSA-N

SMILES: C(C[C@@H](C(=NCC(=N[C@@H](CC(=O)O)C(=N[C@@H](CO)C(=O)O)O)O)O)N=C(CN)O)CNC(=N)N

Synonyme:

• H-Gly-Arg-Gly-Asp-Ser-OH
• glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-serine

H-Gly-Arg-Gly-Asp-Ser-OH

CAS: 96426-21-0

GRGDS, a fragment derived from the cell binding region of fibronectin. Inhibitor of thrombin-induced platelet aggregation.

Formel: C₁₇H₃₀N₈O₉

Reinheit: 96.7%

Farbe und Form: White Lyophilisate

Molekulargewicht: 490.47

Ref: 01-4008998

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Gly-Arg-Gly-Asp-Ser (GRGDS) is a synthetic fibronectin-derived pentapeptide. Its RGD core mediates cell adhesion and inhibits ACE activity.

Formel: C₁₇H₃₀N₈O₉

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 490.4683

Ref: TM-TP1459

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Formel: C₁₇H₃₀N₈O₉

Molekulargewicht: 490.47

Ref: 7W-GL3717

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Gly-Arg-Gly-Asp-Ser

Formel: C₁₇H₃₀N₈O₉

Reinheit: ≥95%

Molekulargewicht: 490.47

Ref: 54-OR1134024

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Formel: C₁₇H₃₀N₈O₉

Reinheit: 98%

Molekulargewicht: 490.4683

Ref: IN-DA019FVU

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials.

Formel: C₁₇H₃₀N₈O₉CH₃COOHH₂O

Reinheit: Min. 95%

Molekulargewicht: 490.47 g/mol

Ref: 3D-PFA-4189

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials. This product is available as a 0.5mg vial.

Formel: C₁₇H₃₀N₈O₉

Reinheit: Min. 95%

Molekulargewicht: 490.47 g/mol

Ref: 3D-PFA-4189-V

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt

CAS: 96426-21-0

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt is a synthetic peptide that is designed to bind to the nuclear factor kappa B (NFκB) and inhibit its activation. NFκB is a transcription factor that regulates gene expression in response to various stimuli, including proinflammatory cytokines, oxidants, and electrophilic compounds. H-Gly-Arg-Gly-Asp-Ser-OH TFA salt has been shown to inhibit NFκB activation in a model system. This molecule also inhibits axonal growth and pluripotent cells differentiation, which may be due to its suppression of the signal peptide. The rate constant for this drug has been measured using polymer compositions and biocompatible polymers.

Formel: C₁₇H₃₀N₈O₉(freebase)

Reinheit: Min. 95%

Molekulargewicht: 490.47 g/mol

Ref: 3D-FG108418