CAS 99290-97-8

(1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-10-[(2,6-Didesoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-tridesoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-7,16-dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-on

Formel: C₃₇H₆₆N₂O₁₂

InChl: InChI=1S/C37H66N2O12/c1-14-25-37(10,44)29(41)22(6)38-32-18(2)16-36(9,51-32)31(50-34-27(40)24(39(11)12)15-19(3)46-34)20(4)28(21(5)33(43)48-25)49-26-17-35(8,45-13)30(42)23(7)47-26/h18-31,34,40-42,44H,14-17H2,1-13H3/b38-32-/t18-,19-,20+,21-,22-,23+,24+,25-,26+,27-,28+,29-,30+,31-,34+,35-,36-,37-/m1/s1

InChI Key: InChIKey=BPENQAXMHXRNMD-ULJZSMOKSA-N

SMILES: O([C@H]1[C@]2(C)O/C(/[C@H](C)C2)=N\[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3)[C@@H]1C)[C@H]4[C@H](O)[C@@H](N(C)C)C[C@@H](C)O4

Synonyme:

• (1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-10-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-7,16-dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one
• 7,16-Dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one, 10-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4R*,5S*,6R*,9R*,10S*,11S*,12R*,13R*,15R*)]-
• 7,16-Dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one, 10-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-

Erythromycin A (6,9-Imino Ether)

CAS: 99290-97-8

Formel: C₃₇H₆₆N₂O₁₂

Farbe und Form: White To Off-White Solid

Molekulargewicht: 730.94

Ref: 4Z-E-207

Erythromycin A 6,9-Imino Ether

CAS: 99290-97-8

Stability Hygroscopic
Applications An impurity in the synthesis of Erythromycin (E649950). An antibacterial.
References Zhang, L. et al.: J. Antibio., 64, 243 (2011); Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

Formel: C₃₇H₆₆N₂O₁₂

Farbe und Form: Neat

Molekulargewicht: 730.93

Ref: TR-E650015

Erythromycin A 6,9-imino ether

CAS: 99290-97-8

Erythromycin is a macrolide antibiotic that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to have antibacterial activity against both staphylococci and streptococci. Erythromycin binds to the 23S ribosomal RNA, which prevents protein synthesis and cell division. The drug is used for the treatment of infections caused by bacteria susceptible to erythromycin, such as Group P2 (Streptococcus pneumoniae) and Group A (Staphylococcus aureus). Erythromycin also inhibits the biosynthesis of macrolactones, which are antibiotics related to erythromycin. These compounds are found in Streptomyces spp., Actinomycetes spp., and Mycobacterium smegmatis.

Formel: C₃₇H₆₆N₂O₁₂

Reinheit: Min. 95%

Farbe und Form: White To Off-White Solid

Molekulargewicht: 730.93 g/mol

Ref: 3D-FE146285

Erythromycin A Imino ether

CAS: 99290-97-8

Formel: C₃₇H₆₆N₂O₁₂

Molekulargewicht: 730.94

Ref: ST-EA-CP-E18023