p38 MAPK
p38 MAPKs sind eine Untergruppe der MAPKs, die auf Stresssignale reagieren und an der Regulation von Entzündungen, Zelldifferenzierung, Apoptose und Autophagie beteiligt sind. Die p38 MAPK-Signalübertragung ist entscheidend für Immunantworten und wird mit verschiedenen Krankheiten in Verbindung gebracht, einschließlich chronisch entzündlicher Erkrankungen, Krebs und neurodegenerativen Störungen. Bei CymitQuimica bieten wir eine umfassende Auswahl an p38 MAPK-Inhibitoren und Modulatoren zur Unterstützung Ihrer Forschung in den Bereichen Entzündung, Stressreaktion und therapeutische Entwicklung an.
112 Produkte aus dem Bereich "p38 MAPK" gefunden
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AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formel:C27H30FN5O3Reinheit:98.82%Farbe und Form:SolidMolekulargewicht:491.56Ref: TM-T14381
1mg70,00€5mg152,00€10mg236,00€25mg432,00€50mg647,00€100mg964,00€1mL*10mM (DMSO)166,00€Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formel:C9H8O4Reinheit:99.78% - 99.91%Farbe und Form:White Solid CrystallineMolekulargewicht:180.16SB220025
CAS:SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits angiogenesis.Formel:C18H19FN6Reinheit:99.44%Farbe und Form:SolidMolekulargewicht:338.38Carbimazole
CAS:Carbimazole, an imidazolium-based thyroid blocker, turns to MMI in the body. Used in Graves' disease research.Formel:C7H10N2O2SReinheit:99.98%Farbe und Form:SolidMolekulargewicht:186.23Dihydrocaffeic acid
CAS:Dihydrocaffeic acid, a chlorogenic acid metabolite, has antioxidant, anti-Alzheimer's, neuroprotective, and lipid-lowering properties.Formel:C9H10O4Reinheit:98.63%Farbe und Form:SolidMolekulargewicht:182.17BI-3406
CAS:BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.Formel:C23H25F3N4O3Reinheit:99.2% - 99.66%Farbe und Form:SolidMolekulargewicht:462.46Ref: TM-T12979
1mg73,00€5mg160,00€10mg250,00€25mg464,00€50mg663,00€100mg919,00€500mg1.833,00€1mL*10mM (DMSO)170,00€Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formel:C8H12ClNO3Reinheit:98.34% - 99.85%Farbe und Form:Physical Description Beige Solid (Ntp 1992)Molekulargewicht:205.64Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formel:C22H24ClNO4Reinheit:99.53%Farbe und Form:SolidMolekulargewicht:401.88Ref: TM-T10990
1mg55,00€5mg105,00€10mg152,00€25mg250,00€50mg375,00€100mg533,00€1mL*10mM (DMSO)117,00€Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formel:C8H12BrNO3Reinheit:98.22% - 99.88%Farbe und Form:Beige To Brown Fine Crystalline PowderMolekulargewicht:250.09LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formel:C25H25F3N4O4Reinheit:98.3% - 99.92%Farbe und Form:SolidMolekulargewicht:502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Formel:C23H19F3N4O3Reinheit:97.53%Farbe und Form:SolidMolekulargewicht:456.42PF-3644022
CAS:PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.Formel:C21H18N4OSReinheit:98.13%Farbe und Form:SolidMolekulargewicht:374.46Ref: TM-T16501
1mg37,00€5mg111,00€10mg202,00€25mg416,00€50mg620,00€100mg832,00€500mg1.663,00€1mL*10mM (DMSO)187,00€Hesperetin
CAS:Hesperetin belongs to the flavanone class of flavonoids.Formel:C16H14O6Reinheit:98.45% - 99.27%Farbe und Form:SolidMolekulargewicht:302.28Klotho-derived peptide 1 hydrochloride
Klotho-derived peptide 1 (KP1 human) hydrochloride inhibits the interaction between TGF-β and TGF-β receptor 2, suppressing the activation of TGF-β-induced Smad2/3 and mitogen-activated protein kinase (MAPK). Additionally, it exhibits antifibrotic and renal protective effects in mouse models.Farbe und Form:Odour SolidNR-11c
NR-11c is a selective and potent p38α PROTAC degrader. It effectively degrades p38α in various tumor cells. When administered to mice via intraperitoneal or tail vein injection, NR-11c primarily acts in the liver. It is used for cancer research.Formel:C59H71BrF2N10O8SMolekulargewicht:1198.22MAP3K5-IN-1
CAS:Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].Formel:C28H24N4O4Farbe und Form:SolidMolekulargewicht:480.51Cyclotraxin B
CAS:TrkB receptor antagonist; inhibits BDNF-TrkB signaling (IC50 = 0.30 nM); alters receptor shape; may reduce anxiety in mice.
Formel:C48H73N13O17S3Reinheit:98%Farbe und Form:SolidMolekulargewicht:1200.36p38 MAP Kinase Inhibitor Ⅵ
CAS:p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.Formel:C16H13FN2OS2Reinheit:98.53%Farbe und Form:SolidMolekulargewicht:332.42PDE4-IN-26
PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.Formel:C22H18F2N4O3SFarbe und Form:SolidMolekulargewicht:456.47DB-10
DB-10 serves as a precursor to 3-nbutylphthalide (NBP). It is absorbed by cells in a temperature and energy-dependent manner through the pyrilamine cation transporter. DB-10 enhances cell survival and rapidly converts into an active form in vivo, increasing accumulation within the brain. This compound is applicable in ischemic stroke research.Farbe und Form:Odour Solid
