Transporter/Ionenkanal

Levamlodipine (S-amlodipine) belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as …

GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM …

Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.

Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by …

Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. …

Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246 µM and 0.197 µM for hNKCC1A and …

Elexacaftor (VX-445) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also …

Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It …

Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith …

Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of …

CRAC intermediate 1 is a key intermediate used in the synthesis of the CRAC ion …

Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin …

(-)-Sparteine sulfate pentahydrate ((-)-Sparteine Sulfate) is a class 1a antiarrhythmic agent and a sodium channel …

Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little …

Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.

Gut restricted-7 (GR-7) (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. …

Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.

Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the …

Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide …

5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE.

BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 …

Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.

Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective …

Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local …

NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small …

Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve …

A 438079 is a potent, and selective antagonist of P2X7 receptor (pIC50: 6.9).

Vigabatrin (Sabril), an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate Transaminase responsible …

Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class …

Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium …

Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.

Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.

GV-58 is a selective N- and P/Q-type Ca2+ channels agonist (EC50: 7.21/8.81 uM for N-type/P-Q-type …

Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas …

FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit …

Cinnarizine (Stugeron) is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating …

Penfluridol (TLP-607) is a highly potent antipsychotic.

Betaine chloride (Betaine hydrochloride) is an acidic form of betaine, a vitamin-like substance observed in …

Indazole is also called benzpyrazole or isoindazone. Its derivatives exhibit a wide range of biological …

Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type …

Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain …

(+)-Camphor (D-Camphor) is the oil extracted from the wood of the Camphor tree Cinnamomum Camphora …

ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 …

Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.

Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 …

Dantrolene sodium (Lapatinib ditosylate monohydrate) salt is a skeletal muscle relaxant and can interfere with …

AZD9056 hydrochloride is a P2X7 inhibitor,Which plays a significant role in pain-causing diseases and inflammation.

Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not …

Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the …

Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow …

Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.