Transporter/Ionenkanal

BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.

Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of …

Isoxsuprine hydrochloride (Isolait) is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular …

Lappaconitine ((+)-Lappaconitine), isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.

NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in …

Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific …

DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel …

Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of …

Halazone is fine white powder with an odor of chlorine. It has been widely used …

Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .

Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of …

TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 …

Amlodipine (UK-48340) is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal …

Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 …

Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has …

Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers …

CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.

Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.

Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.

Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those …

Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.

Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.

Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and …

VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel …

PEPA is an allosteric AMPA receptors modulator; binds to the GluA2o and GluA3o LBDs and …

Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic …

Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the …

Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist …

Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple …

Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of …

Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx …

Lidocaine hydrochloride (Lignocaine hydrochloride) is a local anesthetic and cardiac depressant used as an antiarrhythmic …

Nilvadipine (FK235), a calcium channel blocker (CCB), is utilized for treatment of hypertension.

(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic …

Encequidar mesylate (HM30181A mesylate) is a competitive P-glycoprotein inhibitor.

Azelnidipine (UR-12592) is a dihydropyridine used as calcium channel blocker.

Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in …

Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an …

Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It …

(-)-Sparteine sulfate pentahydrate ((-)-Sparteine Sulfate) is a class 1a antiarrhythmic agent and a sodium channel …

Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.

Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.

NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small …

Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve …

FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit …

(+)-Camphor (D-Camphor) is the oil extracted from the wood of the Camphor tree Cinnamomum Camphora …

Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the …

Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow …

GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of …

NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 …

NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM. NS19504 shows …

Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat …

Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of …