2-Aminopyrimidine-5-boronic acid pinacol ester

CAS: 402960-38-7

Ref. 3D-FA33574

Produktinformation

• Name: 2-Aminopyrimidine-5-boronic acid pinacol ester
• Synonyme: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine, 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidin-2-Amine
• CAS: 402960-38-7

Beschreibung

2-Aminopyrimidine-5-boronic acid pinacol ester is a boronic acid derivative that has been shown to inhibit the activity of protein kinase C. This compound is also an effective linker for cross-coupling reactions and has a low reactivity with nucleophiles, which makes it safer than other boronic acids. 2-Aminopyrimidine-5-boronic acid pinacol ester has been shown to be potent against cancer cells in vitro and in vivo and synthetic cells. 2-Aminopyrimidine-5-boronic acid pinacol ester inhibits the growth of cancer cells by binding to the ATP site on protein kinase C, thereby inhibiting its function.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 221.06 g/mol
• Formel: C₁₀H₁₆BN₃O₂
• Reinheit: Min. 95 Area-%
• Farbe/Form: Powder
• InChl: InChI=1S/C10H16BN3O2/c1-9(2)10(3,4)16-11(15-9)7-5-13-8(12)14-6-7/h5-6H,1-4H3,(H2,12,13,14)
• InChI Key: InChIKey=BPQVMIDUTRJYSC-UHFFFAOYSA-N
• SMILES: CC1(C)OB(c2cnc(N)nc2)OC1(C)C