5-Formylindole

CAS: 1196-69-6

Ref. 3D-FF16209

Produktinformation

• Name: 5-Formylindole
• Synonyme: Indole-5-carboxaldehyde, 1H-indole-5-carbaldehyde, 1H-indole-6-carbaldehyde, 5-Indolealdehyde, 1H-Indole-5-carboxaldehyde

Beschreibung

5-Formylindole is a non-selective and irreversible inhibitor of protein α, which is the catalytic subunit of the enzyme AMP-activated protein kinase. It binds to the hydroxyl group at position Cys177 in the ATP binding pocket of protein α, thereby inhibiting its activity. 5-Formylindole has been shown to inhibit tumor growth in xenografts and also inhibits fat accumulation in 3T3-L1 preadipocytes by inhibition of fatty acid synthesis. This compound has also been used to study molecular modeling in order to understand hydrogen bond interactions between aldehyde groups and intramolecular hydrogen. The genus that this compound belongs to is stilbene derivatives.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 145.16 g/mol
• Formel: C₉H₇NO
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C9H7NO/c11-6-7-1-2-9-8(5-7)3-4-10-9/h1-6,10H
• InChI Key: InChIKey=ADZUEEUKBYCSEY-UHFFFAOYSA-N
• SMILES: O=Cc1ccc2[nH]ccc2c1