Cetirizine impurity B dihydrochloride

CAS: 1000690-91-4

Ref. 3D-IC46026

Produktinformation

• Name: Cetirizine impurity B dihydrochloride
• Synonyme: De(carboxymethoxy) cetirizine acetic acid dihydrochloride
• Marke: Biosynth
• Beschreibung: Cetirizine impurity B dihydrochloride is a minor impurity of cetirizine, which is a non-sedating antihistamine. The purity of the compound was determined by high performance liquid chromatography (HPLC) and its bioequivalence to cetirizine was assessed in a population pharmacokinetic study. Cetirizine impurity B dihydrochloride has been shown to have a similar pharmacokinetic profile to cetirizine and can be used as an alternative for the treatment of allergic rhinitis.

Chemische Eigenschaften

• Molekulargewicht: 417.76 g/mol
• Formel: C₁₉H₂₁ClN₂O₂•(HCl)₂
• Reinheit: Min. 90 Area-%
• Farbe/Form: Powder
• InChl: InChI=1S/C19H21ClN2O2/c20-17-8-6-16(7-9-17)19(15-4-2-1-3-5-15)22-12-10-21(11-13-22)14-18(23)24/h1-9,19H,10-14H2,(H,23,24)
• InChI Key: InChIKey=NBQBQRKLQXVPIS-UHFFFAOYSA-N
• SMILES: O=C(O)CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1