
CAS 1000690-91-4
:Formel:C19H23Cl3N2O2
InChl:InChI=1S/C19H21ClN2O2.2ClH/c20-17-8-6-16(7-9-17)19(15-4-2-1-3-5-15)22-12-10-21(11-13-22)14-18(23)24;;/h1-9,19H,10-14H2,(H,23,24);2*1H
InChI Key:LSPZEDLYSAUAQV-UHFFFAOYSA-N
SMILES:C1CN(CCN1CC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
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Cetirizine EP Impurity B DiHCl
CAS:Formel:C19H21ClN2O2·2HClFarbe und Form:White To Off-White SolidMolekulargewicht:344.84 2*36.46Cetirizine Impurity B dihydrochloride
CAS:Cetirizine Impurity B dihydrochloride
Reinheit:≥95%Molekulargewicht:417.76g/mol(RS)-2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]acetic Acid Dihydrochloride
CAS:Farbe und Form:NeatDe(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
CAS:Kontrolliertes ProduktApplications De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic.
References De Vos, C., et al.: Ann. Allergy, 59, 278 (1987); Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987); Fadel, R., et al.: Clin. Allergy, 17, 373 (1987); Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)Formel:C19H21ClN2O2•2HClFarbe und Form:NeatMolekulargewicht:417.76Cetirizine Impurity B dihydrochloride
CAS:Cetirizine Impurity B dihydrochloride is a Cetirizine antihistamine byproduct with anti-allergic properties.Formel:C19H23Cl3N2O2Reinheit:97.33%Farbe und Form:SolidMolekulargewicht:417.76Cetirizine impurity B dihydrochloride
CAS:Cetirizine impurity B dihydrochloride is a minor impurity of cetirizine, which is a non-sedating antihistamine. The purity of the compound was determined by high performance liquid chromatography (HPLC) and its bioequivalence to cetirizine was assessed in a population pharmacokinetic study. Cetirizine impurity B dihydrochloride has been shown to have a similar pharmacokinetic profile to cetirizine and can be used as an alternative for the treatment of allergic rhinitis.Formel:C19H21ClN2O2•(HCl)2Reinheit:Min. 90 Area-%Farbe und Form:PowderMolekulargewicht:417.76 g/molRef: 3D-IC46026
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