5-Bromo-2'-deoxycytidine

CAS: 1022-79-3

Ref. 3D-NB06450

Produktinformation

• Name: 5-Bromo-2'-deoxycytidine
• Synonyme: 5-Bromo-2'-deoxy-D-cytidine
• Marke: Biosynth
• Beschreibung: 5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is structurally similar to cytidine, and inhibits the enzyme DNA polymerase by intramolecular catalysis. This causes deamination of the 5-bromo group, which prevents further synthesis of DNA. 5-Bromo-2'-deoxycytidine has been shown to be effective in vivo in a mouse model for inflammatory bowel diseases, including colitis and eosinophilic enteritis. The drug was also found to inhibit the production of Eosinophil peroxidase from HL-60 cells in vitro.

Chemische Eigenschaften

• Molekulargewicht: 306.11 g/mol
• Formel: C₉H₁₂BrN₃O₄
• Reinheit: Min. 95%
• Farbe/Form: Off-White Powder