5-Carboxy-2'-deoxyuridine

CAS: 14599-46-3

Ref. 3D-NC58344

Produktinformation

• Name: 5-Carboxy-2'-deoxyuridine
• Synonyme: Trifluridine Related Compound A, 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid, 2'-Deoxy-5-carboxyuridine, 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-, 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-, Uridine, 5-Carboxy-2'-Deoxy-

Beschreibung

5-Carboxy-2'-deoxyuridine is a nucleoside analogue that inhibits herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) replication. It is used to treat genital herpes infections caused by HSV-1 or HSV-2. 5-Carboxy-2'-deoxyuridine has been shown to inhibit the growth of human cancer cells in culture, and is currently being investigated as a potential anticancer drug. This drug binds with high affinity to the viral DNA polymerase, forming a covalent bond with the uracil base in the viral DNA chain. This prevents further elongation of the chain, inhibiting viral replication. 5-Carboxy-2'-deoxyuridine also inhibits cellular protein synthesis and cell division, which may be due to its ability to bind with aldehyde groups on surfactant proteins.END>

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 272.21 g/mol
• Formel: C₁₀H₁₂N₂O₇
• Reinheit: Min. 95%
• Farbe/Form: Powder