GNF-7

CAS: 839706-07-9

Ref. 3D-PIB70607

Produktinformation

• Name: GNF-7
• CAS: 839706-07-9

Beschreibung

GNF-7 is a molecule that inhibits the bcr-abl kinase, which plays a key role in chronic myelogenous leukemia (CML) and some other cancers. GNF-7 binds to the ATP binding site of the bcr-abl kinase, inhibiting its activity. It also induces caspase-independent cell death by hydrogen bond interactions with amino acids in the ATP binding site. The study has shown that GNF-7 is effective on monocytes, myeloid leukemia cells, and inflammatory bowel disease cells. GNF-7 is a small molecule that can be synthesized by chemical methods and is thus cheaper than many other cancer drugs.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 547.53 g/mol
• Formel: C₂₈H₂₄F₃N₇O₂
• Reinheit: Min. 95%