5-Azacytidine

CAS: 320-67-2

Ref. TR-A796000

Produktinformation

• Name: 5-Azacytidine
• Synonyme: 5-AZC, 5-AZCR, 5-AzaC, Antibiotic U 18496, Azacitidine, Azacytidine, Ladakamycin, Ledakamycin, Mylosar, NSC 102816, NSC 103-627, U 18496, Vidaza, WR 183027,5-AC, 4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one, s-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl- (8CI), 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-D-ribofuranosyl-, 2-(β-D-Ribofuranosyl)-4-amino-1,3,5-triazin-2-on, 2-(β-D-ribofurannosyl)-4-amino-1,3,5-triazine-2-one, 2-(β-D-ribofuranosil)-4-amino-1,3,5-triazin-2-ona, 2-(β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2-one, 4-Amino-1-Beta-D-Ribofuranosyl-S-Triazin-2(1H)-On, 4-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1,3,5-triazin-2(1H)-one, 4-amino-1-D-lyxofuranosyl-1,3,5-triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one, 4-amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one, 5 Azc, 5-Ac, 5-Azac, 5-Azacitidine, 5-Azcr, 5-Triazin-2(1H)-One,4-Amino-1-Beta-D-Ribofuranosyl-3, Antibiotic u 18496, Antibioticu18496, Cc 486, Nci-C01569, Nsc 103-627, Nsc-102816, U18496, Wr 183027, s-Triazin-2(1H)-one, 4-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, s-Triazin-2(1H)-one, 4-amino-1-β-D-ribofuranosyl-, 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Beschreibung

Applications A potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.
References Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 244.20
• Formel: C₈H₁₂N₄O₅
• Farbe/Form: Off-White
• InChl: InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1
• InChI Key: InChIKey=NMUSYJAQQFHJEW-KVTDHHQDSA-N
• SMILES: Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1