Fialuridine

CAS: 69123-98-4

Ref. TR-F335000

Produktinformation

• Name: Fialuridine
• Synonyme: 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione, 1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-iodouracil, 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione, 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodouracil, 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione, 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione, 1-(2-Deoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione, 1-(2-Deoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-arabinofuranosyl)-5-iodouracil, 1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione, 1-(2-deoxy-2-fluoropentofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione, 1-[(2R,3S,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-5-Iodopyrimidine-2,4-Dione, 2'-Fluoro-5-Iodo-2'-Deoxyuridine, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-arabinofuranosyl)-5-iodo-, 2,4(1H,3H)-pyrimidinedione, 1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodo-, 2,4(1H,3H)-pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-, 5-Iodo-2'-fluoro-2'-deoxy-ara-uridine, 5-Iodo-2'-fluoro-deoxyuridine, 5-Iodo-2'-fluoroarauracil, Fluoroiodoarauracil, NSC 678514
• CAS: 69123-98-4

Beschreibung

Applications An antiviral agent; nucleoside analog with antihepatitis B activity.
References Watanabe A., et al.: J. Med. Chem., 22, 21 (1979), Colacino, J.M., et al.: Antimicrob. Agents Chemother., 24, 505 (1983), Staschke, K.A., et al.: Antiviral Res., 23, 45 (1994), Cui, L., et al.: J. Clin. Invest., 95, 555 (1995),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 372.09
• Formel: C₉H₁₀FIN₂O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5+,6-,8-/m1/s1
• InChI Key: InChIKey=IPVFGAYTKQKGBM-BYPJNBLXSA-N
• SMILES: O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F)cc1I